CNOT11

CNOT11
Identifiers
Aliases	CNOT11, C2orf29, C40, CCR4-NOT transcription complex subunit 11
External IDs	MGI: 106580; HomoloGene: 9711; GeneCards: CNOT11; OMA:CNOT11 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q11.2 Start 101,252,886 bp End 101,270,316 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 B|1 18.31 cM Start 39,574,073 bp End 39,585,970 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte mucosa of ileum myocardium of left ventricle tibialis anterior muscle rectum body of pancreas mucosa of transverse colon cardiac muscle tissue of right atrium granulocyte Top expressed in primary oocyte secondary oocyte hand epiblast spermatocyte zygote interventricular septum superior cervical ganglion endocardial cushion Gonadal ridge More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding molecular function Cellular component cytoplasm cytosol nucleus CCR4-NOT complex Biological process nuclear-transcribed mRNA poly(A) tail shortening gene silencing cell population proliferation regulation of transcription, DNA-templated regulation of translation transcription, DNA-templated DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55571 52846 Ensembl ENSG00000158435 ENSMUSG00000003135 UniProt Q9UKZ1 Q9CWN7 RefSeq (mRNA) NM_017546 NM_028043 RefSeq (protein) NP_060016 NP_082319 Location (UCSC) Chr 2: 101.25 – 101.27 Mb Chr 1: 39.57 – 39.59 Mb PubMed search
Wikidata
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CCR4-NOT transcription complex subunit 11 is a protein that in humans is encoded by the CNOT11 gene. It is a subunit of the CCR4-Not deadenylase complex.

Further reading

• Mauxion F, Prève B, Séraphin B (February 2013). "C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex". RNA Biol. 10 (2): 267–76. doi:10.4161/rna.23065. PMC 3594285. PMID 23232451.