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In molecular biology, CLRN1 antisense RNA 1 (CLRN1-AS1) (previously known as clarin 1 opposite strand, CLRN1OS or USH critical region pseudogene, UCRP) is a human gene encoding a long non-coding RNA. It was originally identified in a screen to identify the genes responsible for Usher syndrome type 3 and presumed to be an unprocessed pseudogene.[2]