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Bisnortilidine

From Wikipedia, the free encyclopedia
Bisnortilidine
Names
Preferred IUPAC name
Ethyl (1R,2S)-2-amino[1,1′-bi(cyclohexane)]-1′,3,3′,5′-tetraene-1-carboxylate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C15H19NO2/c1-2-18-14(17)15(11-7-6-10-13(15)16)12-8-4-3-5-9-12/h3-6,8-10,13H,2,7,11,16H2,1H3/t13-,15+/m0/s1
    Key: BTKAMSWFNMGLGM-DZGCQCFKSA-N
  • CCOC(=O)[C@]1(CCC=C[C@@H]1N)C2=CC=CC=C2
Properties
C15H19NO2
Molar mass 245.322 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Bisnortilidine is an opioid metabolite.[1] It is formed from tilidine by demethylation in the liver.

References

[edit]
  1. Wustrow, I.; Riedel, K. D.; Mikus, G.; Weiss, J. (2012). "In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine". Naunyn-Schmiedeberg's Archives of Pharmacology. 385 (6): 633–9. doi:10.1007/s00210-012-0737-z. PMID 22349139. S2CID 2660215.