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BIDN

From Wikipedia, the free encyclopedia
BIDN
Names
IUPAC name
3,3-Bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
Other names
Flucybene
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C11H8F6N2/c12-10(13,14)9(11(15,16)17)7-2-1-6(3-7)8(9,4-18)5-19/h6-7H,1-3H2
    Key: MUIBMWREADMFQF-UHFFFAOYSA-N
  • C1CC2CC1C(C2(C(F)(F)F)C(F)(F)F)(C#N)C#N
Properties
C11H8F6N2
Molar mass 282.189 g·mol−1
Hazards
GHS labelling:
GHS06: Toxic
Danger
H300
P264, P270, P301+P310, P321, P330, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

BIDN is an insecticide with a structure related to norbornane. It functions as a GABA receptor antagonist and convulsant.[1]

Further reading

[edit]
  • Chen, Ligong; Durkin, Kathleen A.; Casida, John E. (2006). "Structural model for γ-aminobutyric acid receptor noncompetitive antagonist binding: Widely diverse structures fit the same site". Proceedings of the National Academy of Sciences. 103 (13): 5185–5190. doi:10.1073/pnas.0600370103. PMC 1458815. PMID 16537435.
  • Zhao, Chunqing; Hwang, Sung Hee; Buchholz, Bruce A.; Carpenter, Timothy S.; Lightstone, Felice C.; Yang, Jun; Hammock, Bruce D.; Casida, John E. (2014). "GABAAreceptor target of tetramethylenedisulfotetramine". Proceedings of the National Academy of Sciences. 111 (23): 8607–8612. doi:10.1073/pnas.1407379111. PMC 4060666. PMID 24912155.

See also

[edit]

References

[edit]
  1. Rauh, James J; Holyoke, Caleb W; Kleier, Daniel A; Presnail, James K; Benner, Eric A; Cordova, Daniel; Howard, Michael H; Hosie, Alastair M; Buckingham, Steven D; Baylis, Howard A; Sattelle, David B (1997). "Polycyclic dinitriles: a novel class of potent GABAergic insecticides provides a new radioligand, [3H]BIDN". Invertebrate Neuroscience. 3 (2–3): 261–8. doi:10.1007/bf02480383. PMID 9783448. S2CID 33478021.