APOL6

APOL6
Identifiers
Aliases	APOL6, APOL-VI, APOLVI, apolipoprotein L6
External IDs	OMIM: 607256; MGI: 1919189; HomoloGene: 49940; GeneCards: APOL6; OMA:APOL6 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	35,668,404 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	76,941,306 bp
RNA expression pattern
	Top expressed in
	pericardium; ; pylorus; ; sperm; ; buccal mucosa cell; ; monocyte; ; epithelium of colon; ; epithelium of nasopharynx; ; human penis; ; vena cava; ; cardia;
	Top expressed in
	white adipose tissue; ; subcutaneous adipose tissue; ; soleus muscle; ; brown adipose tissue; ; muscle of thigh; ; mammary gland; ; zygote; ; skeletal muscle tissue; ; intercostal muscle; ; thoracic diaphragm;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	lipid binding;
Cellular component	extracellular region; cytoplasm;
Biological process	lipoprotein metabolic process; lipid transport;
	Sources:Amigo / QuickGO
Orthologs
	80830
	71939
	ENSG00000221963
	ENSMUSG00000033576
	Q9BWW8
	n/a
	NM_030641
	NM_001163621; NM_028010
	NP_085144
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Apolipoprotein L6 is a protein that in humans is encoded by the APOL6 gene.^[5]^[6]^[7]

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000221963 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033576 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". Genomics. 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903.
↑ Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells". Mol Cancer Res. 3 (1): 21–31. doi:10.1158/1541-7786.21.3.1. PMID 15671246. S2CID 2545675.
1 2 "Entrez Gene: APOL6 apolipoprotein L, 6".

External links

Human APOL6 genome location and APOL6 gene details page in the UCSC Genome Browser.

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Dominguez O, Ashhab Y, Sabater L, et al. (1999). "Cloning of ARE-containing genes by AU-motif-directed display". Genomics. 54 (2): 278–86. doi:10.1006/geno.1998.5548. PMID 9828130.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000221963 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033576 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11374903-5] Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". Genomics. 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903.

[pmid15671246-6] Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells". Mol Cancer Res. 3 (1): 21–31. doi:10.1158/1541-7786.21.3.1. PMID 15671246. S2CID 2545675.

[entrez-7] 1 2 "Entrez Gene: APOL6 apolipoprotein L, 6".

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This page was redesigned at the edge.

APOL6

References

External links

Further reading