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APINAC

From Wikipedia, the free encyclopedia

APINAC
Clinical data
Other namesAKB-57, AKB57
Legal status
Legal status
Identifiers
  • N-(1-Adamantyl)-1-pentylindazole-3-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H31N2O2
Molar mass367.513 g·mol−1
3D model (JSmol)
  • CCCCCn1nc(C(=O)OC23CC4CC(CC(C4)C2)C3)c2ccccc21
  • InChI=1S/C23H30N2O2/c1-2-3-6-9-25-20-8-5-4-7-19(20)21(24-25)22(26)27-23-13-16-10-17(14-23)12-18(11-16)15-23/h4-5,7-8,16-18H,2-3,6,9-15H2,1H3
  • Key:KCCVWUAAHDXNNQ-UHFFFAOYSA-N

APINAC (AKB-57, N-(1-adamantyl)-1-pentylindazole-3-carboxylate) is a drug that acts as an agonist for the cannabinoid receptors.[2] It was detected in Slovenia in 2016[3] and is on the UNODC list of synthetic cannabinoids.[4]

Legality

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APINAC is covered by the UK blanket ban on synthetic cannabinoids.

Detection

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APINAC can be bought by labs as a reference standard.[5] APINAC metabolizes to N-pentylindazole-3-carboxylic acid, hydroxylated N-pentylindrazole-3-carboxylic acid, and 1-adamantanol in rats.[2]

See also

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References

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  1. Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
  2. 1 2 Savchuk S, Appolonova S, Pechnikov A, Rizvanova L, Shestakova K, Tagliaro F (2017-07-01). "In vivo metabolism of the new synthetic cannabinoid APINAC in rats by GC–MS and LC–QTOF-MS". Forensic Toxicology. 35 (2): 359–368. doi:10.1007/s11419-017-0364-y. ISSN 1860-8973.
  3. "Analytical Report, AKB-57 (C23H30N2O2)" (PDF). NPS AND RELATED COMPOUNDS DATABASE. Slovenian National Forensic Laboratory (NFL) (published 2016-02-12). 2016-02-04. adamantan-1-yl 1-pentyl-1H-indazole-3-carboxylate; KCCVWUAAHDXNNQ-UHFFFAOYSA-N
  4. "Substance Details AKB-57". www.unodc.org. Retrieved 2026-06-26.
  5. "Apinac (CAS 2219331-93-6)". Cayman. Retrieved 2026-06-26.