RCOR3
REST corepressor 3 (CoREST3) is a protein that in humans is encoded by the RCOR3 gene.[4] It is a member of the CoREST family of corepressor proteins that plays a scaffolding role in stabilizing the REST / CoREST / LSD1 / HDAC complex. This complex's function is to down regulate gene expression.[4]
CoREST3 has been proposed as a biomarker of hepatitis B infection prognosis.[5]
References
[edit]- 1 2 3 GRCh38: Ensembl release 89: ENSG00000117625 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 Maksour S, Ooi L, Dottori M (2020). "More than a Corepressor: The Role of CoREST Proteins in Neurodevelopment". eNeuro. 7 (2). doi:10.1523/ENEURO.0337-19.2020. PMC 7070449. PMID 32075869.
- ↑ Xue JH, Zheng M, Xu XW, Wu SS, Chen Z, Chen F (August 2011). "Involvement of REST corepressor 3 in prognosis of human hepatitis B". Acta Pharmacologica Sinica. 32 (8): 1019–1024. doi:10.1038/aps.2011.49. PMC 4002525. PMID 21765449.
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