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// Workers AI · dad joke modeWhat did Menitrazepam say to stress? "You're always on my mind, but I'll tranquil-ize you.

From Wikipedia, the free encyclopedia
Menitrazepam
Identifiers
  • 5-(cyclohexen-1-yl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H17N3O3
Molar mass299.330 g·mol−1
3D model (JSmol)
  • O=N(C1=CC=C2C(C(C3=CCCCC3)=NCC(N2C)=O)=C1)=O
  • InChI=1S/C16H17N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h5,7-9H,2-4,6,10H2,1H3 checkY
  • Key:CMFUDRPCXZQTOM-UHFFFAOYSA-N checkY
  (verify)

Menitrazepam[1] is a drug which is a benzodiazepine derivative.[2][3] It is similar in structure to tetrazepam and nimetazepam, with the 7-chloro group of tetrazepam replaced by nitro. It is a hypnotic agent used in the treatment of insomnia, and therefore has strong sedative, anticonvulsant, muscle relaxant, and anxiolytic actions like those of other hypnotic benzodiazepines. Menitrazepam is a good oral hypnotic agent, however, delay in the time for peak plasma levels to reach their maximum brings into question the benefit of menitrazepam for the treatment of insomnia when compared to other hypnotics. Typically, the sleep inducing properties of hypnotics occur within 0.5 hours. In some cases, as with temazepam and nitrazepam, strong hypnotic effects can be felt 15 to 20 minutes after oral ingestion.

See also

[edit]

References

[edit]
  1. DE 2017060
  2. Lundbeck Institute: Psychotropics
  3. Volke J, Ellaithy MM, Manousek O (April 1978). "A spectrophotometric and polarographic investigation of three new cyclohexene-substituted benzodiazepines". Talanta. 25 (4): 209–13. doi:10.1016/0039-9140(78)80006-X. PMID 18962241.