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Butomidate

From Wikipedia, the free encyclopedia

Butomidate
Identifiers
  • butyl 3-[1-phenylethyl]imidazole-4-carboxylate
CAS Number
ChemSpider
Chemical and physical data
FormulaC16H20N2O2
Molar mass272.348 g·mol−1
3D model (JSmol)
  • O=C(C1=CN=CN1C(C2=CC=CC=C2)C)OCCCC
  • InChI=1S/C16H20N2O2/c1-3-4-10-20-16(19)15-11-17-12-18(15)13(2)14-8-6-5-7-9-14/h5-9,11-13H,3-4,10H2,1-2H3
  • Key:KZKZZYNLTMCQOW-UHFFFAOYSA-N

Butomidate is an anesthetic drug related to etomidate, which has been sold as a designer drug as an active ingredient in e-cigarette liquids marketed under names such as space oil or kpods. It has an n-butyl ester group in place of the ethyl ester of etomidate.[1][2][3][4]

References

[edit]
  1. Fan Y, Chen X, Wu H, Ke X, Chen H, Xu Y, et al. (November 2025). "Leveraging mass spectrometry fragmentation patterns for accelerated screening and structural elucidation of new etomidate analogues in suspect samples". Journal of Pharmaceutical and Biomedical Analysis. 265 117023. doi:10.1016/j.jpba.2025.117023. PMID 40532400.
  2. Zhang X, Li Y, Liu J, Pan Z, Chen Y, Wang M, et al. (July 2025). "Identification of two novel imidazole-derived GABA agonists butomidate and tf-etomidate in e-cigarette liquids". Forensic Toxicology. doi:10.1007/s11419-025-00732-5. PMID 40643820.
  3. Bai S, Qian Z, Chen Y, Liu S, Wang F, Liu F (September 2025). "Traceability of etomidate and its analogs in biological samples using "specific" metabolites". Analytical Methods. 17 (36): 7207–7216. doi:10.1039/D5AY00773A. PMID 40879556.
  4. "Substance details: Butomidate". UNODC. 2025.