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Microtubule cross-linking factor 3 is a protein in humans that is encoded by the MTCL3gene (previously SOGA3).[5] In contrast to its paralogsMTCL1 and MTCL2, not much has been reported about the function of this protein, but it may be involved in autophagy.[5] It has also been known as suppressor of glucose, autophagy associated 3 (SOGA3).