PGRMC2

PGRMC2
Identifiers
Aliases	PGRMC2, DG6, PMBP, progesterone receptor membrane component 2
External IDs	OMIM: 607735; MGI: 1918054; GeneCards: PGRMC2
Gene location (Human)
Chr.	Chromosome 4 (human)
End	128,288,829 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	41,037,481 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; islet of Langerhans; ; stromal cell of endometrium; ; epithelium of colon; ; skin of abdomen; ; skin of arm; ; skin of leg; ; adipose tissue; ; rectum; ; abdominal fat;
	Top expressed in
	otic placode; ; saccule; ; supraoptic nucleus; ; otic vesicle; ; motor neuron; ; yolk sac; ; skin of external ear; ; Epithelium of choroid plexus; ; seminal vesicula; ; decidua;
	More reference expression data
	n/a
Gene ontology
Molecular function	steroid hormone receptor activity; steroid binding; heme binding; lipid binding; protein binding;
Cellular component	integral component of membrane; nuclear envelope; membrane;
Biological process	steroid hormone mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	10424
	70804
	ENSG00000164040
	ENSMUSG00000049940
	O15173
	Q80UU9
	NM_006320
	NM_027558
	NP_006311
	NP_081834
	Wikidata
View/Edit Human	View/Edit Mouse

Progesterone receptor membrane component 2 (abbreviated PGRMC2) is a protein which is encoded by the PGRMC2 gene.^[5]^[6] It has been detected in the placenta, liver, and spermatozoa, among other areas.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164040 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049940 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Gerdes D, Wehling M, Leube B, Falkenstein E (1998). "Cloning and tissue expression of two putative steroid membrane receptors". Biol. Chem. 379 (7): 907–11. doi:10.1515/bchm.1998.379.7.907. PMID 9705155.
1 2 Lösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E (2005). "Classic and non-classic progesterone receptors are both expressed in human spermatozoa". Horm. Metab. Res. 37 (1): 10–4. doi:10.1055/s-2005-861023. PMID 15702432.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000164040 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049940 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9705155-5] 1 2 Gerdes D, Wehling M, Leube B, Falkenstein E (1998). "Cloning and tissue expression of two putative steroid membrane receptors". Biol. Chem. 379 (7): 907–11. doi:10.1515/bchm.1998.379.7.907. PMID 9705155.

[pmid15702432-6] 1 2 Lösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E (2005). "Classic and non-classic progesterone receptors are both expressed in human spermatozoa". Horm. Metab. Res. 37 (1): 10–4. doi:10.1055/s-2005-861023. PMID 15702432.

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[5]

[6]

See also

References