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Cystocentesis

From Wikipedia, the free encyclopedia

Cystocentesis is a veterinary procedure, mainly performed in dogs and cats, in which a needle is inserted into the urinary bladder through the abdominal wall, and a urine sample is obtained.[1] The clinical procedure can be done either by external palpation and stabilization of the urinary bladder which is called blind cystocentesis or the urinary bladder may be visualized using sonography, while guiding the needle into it, in real time, referred to as ultrasound-guided cystocentesis [2] Cystocentesis has its advantages, although rarely a benign episode of fainting may be triggered by it.[3]

Indications

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Diagnostic cystocentesis is the most common reason to perform the procedure. Commonly practiced in small animal medicine, it provides an uncontaminated urine sample for urinalysis, biochemical assessment, or urine culture for bacterial speciation and antibiotic sensitivity.[4] Diagnostic cystocentesis is used to reduce the risks of bacterial, cellular and debris contamination that other methods (like free catch or catheterization) have.[5] This aids the veterinarian to tailor the treatment plan based on the changes observed in the urine's characteristics and to target antimicrobial treatment to help avoid development of antibiotic resistance by matching the antibiotic to the bacterial sensitivity.[6]

Therapeutic cystocentesis may be employed to relieve pressure buildup due to urethral obstruction i.e. decompressive cystocentesis[7]. Therapeutic cystocentesis is typically a last resort for relief, as a greatly distended bladder is at risk of rupture when punctured. When possible, a safer method of emptying the urinary bladder in this condition is by urethral catheterization.

Research utilizing cystocentesis is mostly focused on the pharmacokinetics of medications, and in studies utilizing biomarkers.[8][9]

References

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  1. "Cystocentesis". Washington State University College of Veterinary Medicine. Archived from the original on 7 October 2013. Retrieved 5 October 2013.
  2. Krawec, Philip; Odunayo, Adesola (2020-05-01). "Performing Cystocentesis in Dogs & Cats: Step-by-Step Guide". Clinician's Brief. Retrieved 2026-08-03.
  3. Odunayo, Adesola; Ng, Zenithson Y.; Holford, Amy Lynn (2015). "Probable vasovagal reaction following cystocentesis in two cats". JFMS open reports. 1 (1) 2055116915585021. doi:10.1177/2055116915585021. ISSN 2055-1169. PMC 5362891. PMID 28491354.
  4. "Urinalysis - Clinical Pathology and Procedures". Merck Veterinary Manual. Retrieved 2026-08-03.
  5. Morgan, Rhea. "Cystocentesis". Wurtsboro Veterinary Clinic. Archived from the original on 6 October 2013. Retrieved 5 October 2013.
  6. Rodrigues, Inês C.; Prata, Joana C.; Pista, Ângela; Costa, Paulo Martins da (2026-01-28). "A Systematic Review of Bacterial Sampling Collection for Veterinary Microbiology in Companion Animals". Veterinary Sciences. 13 (2): 126. doi:10.3390/vetsci13020126. ISSN 2306-7381. PMC 12944951. PMID 41745920.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  7. "Urethral Obstruction in Small Animals - Urinary System". Merck Veterinary Manual. Retrieved 2026-08-03.
  8. Smets, Pascale M. Y.; Meyer, Evelyne; Maddens, Bert; Duchateau, Luc; Daminet, Sylvie (2010-11-01). "Effect of Sampling Method and Storage Conditions on Albumin, Retinol-Binding Protein, And N-Acetyl-β-D-Glucosaminidase Concentrations in Canine Urine Samples". Journal of Veterinary Diagnostic Investigation. 22 (6): 896–902. doi:10.1177/104063871002200607. ISSN 1040-6387.
  9. Warttinger, Ulrich; Krämer, Roland (2018-11-22), Quantification of sulfated polysaccharides in urine by the Heparin Red mix-and-read fluorescence assay, arXiv, doi:10.48550/arXiv.1811.09115, arXiv:1811.09115, retrieved 2026-08-03