WD repeat domain 76

WDR76
Identifiers
Aliases	WDR76, CDW14, WD repeat domain 76
External IDs	MGI: 1926186; HomoloGene: 38573; GeneCards: WDR76; OMA:WDR76 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	43,868,412 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	121,375,341 bp
RNA expression pattern
	Top expressed in
	oocyte; ; ganglionic eminence; ; ventricular zone; ; secondary oocyte; ; endothelial cell; ; testicle; ; gonad; ; Achilles tendon; ; bone marrow cell; ; stromal cell of endometrium;
	Top expressed in
	zygote; ; secondary oocyte; ; superior cervical ganglion; ; primary oocyte; ; tail of embryo; ; thymus; ; genital tubercle; ; ventricular zone; ; epiblast; ; hand;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; enzyme binding;
Cellular component	nucleus; heterochromatin; site of DNA damage;
Biological process	cellular response to DNA damage stimulus; regulation of DNA damage checkpoint;
	Sources:Amigo / QuickGO
Orthologs
	79968
	241627
	ENSG00000092470
	ENSMUSG00000027242
	Q9H967
	A6PWY4
	NM_001167941; NM_024908
	NM_001290986; NM_001290987; NM_030234; NM_001369185
	NP_001161413; NP_079184
	NP_001277915; NP_001277916; NP_084510; NP_001356114
	Wikidata
View/Edit Human	View/Edit Mouse

WD repeat domain 76 is a protein that in humans is encoded by the WDR76 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000092470 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027242 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: WD repeat domain 76". Retrieved 2018-04-16.

Fleischmann C, Bevan S, Neil JC, Terry A, Houlston RS (June 2003). "Mutations in the candidate tumour suppressor gene FLJ12973 on chromosome 15q15 are rare in colorectal cancer". Cancer Lett. 196 (1): 65–7. doi:10.1016/s0304-3835(03)00160-5. PMID 12860291.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.

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