Edge Rewrite
// HTMLRewriter · presentation

This page was redesigned at the edge.

Cloudflare fetched the original article and streamed it through HTMLRewriter to apply an entirely new visual system without rebuilding the source page.

Jump to content

7α-Methyl-19-norandrostenedione

From Wikipedia, the free encyclopedia
(Redirected from Mentabolan)
7α-Methyl-19-norandrostenedione
Clinical data
Other names7α-Methyl-19-norandrost-4-ene-3,17-dione; 7α-Methylestr-4-ene-3,17-dione; MENT dione; Trestione; Mentabolan
Routes of
administration
Oral[1]
Identifiers
  • (7R,8R,9S,10R,13S,14S)-7,13-Dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H26O2
Molar mass286.415 g·mol−1
3D model (JSmol)
  • C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@@H]3[C@@H]1[C@@H]4CCC(=O)[C@]4(CC3)C
  • InChI=1S/C19H26O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h10-11,14-16,18H,3-9H2,1-2H3/t11-,14+,15-,16+,18-,19+/m1/s1
  • Key:IHFREKJAIFEZMQ-ARTWWJDJSA-N

7α-Methyl-19-norandrostenedione (MENT dione), or 7α-methyl-19-norandrost-4-ene-3,17-dione, also known as trestione, as well as 7α-methylestr-4-ene-3,17-dione, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone).[1][2] It may act as a prohormone of trestolone (7α-methyl-19-nortestosterone; MENT).[1][2] MENT dione has been sold on the Internet under the name Mentabolan as a "dietary supplement".[1][2]

Applications

[edit]
  1. If mentabolan is oxidized with a catalytic amount of a copper halide in the presence of oxygen it gives almestrone.[3]
  2. Mentabolan is a precursor in a recent Chinese synthesis of tibolone.[4]
  3. Mentabolan was an intermediate in the original Upjohn synthesis of mibolerone.

See also

[edit]

References

[edit]
  1. 1 2 3 4 Rahnema CD, Crosnoe LE, Kim ED (2015). "Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem". Andrology. 3 (2): 150–5. doi:10.1111/andr.307. PMID 25684733. S2CID 6999218.
  2. 1 2 3 Na, S., Yum, T., Choi, H., Jung, H., Pang, K., & Kim, Y. (2012). Detection of metabolites of mentabolan, a pro-anabolic steroid never marketed, in human urine by GC/MS and GC/MS/MS analysis. 제 49 회 한국분석과학회 추계학술대회, 229-229.
  3. Kuniaki Tatsuta, Kazuo Maruhashi, & Shingo Yano, WO2007049672 (to Taiho Pharmaceutical Co Ltd).
  4. 孙晓明, et al. CN114409717 (2023 to Hunan Keyixin Biomedical Co ltd).