Catenin alpha-3

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Structures	Swiss-model
Domains	InterPro

CTNNA3
CTNNA3
Identifiers
Symbol	CTNNA3
Alt. names	VR22; ARVD13
NCBI gene	29119
HGNC	2511
OMIM	607667
UniProt	Q9UI47
Other data
Locus	Chr. 10 q21.3
Wikidata	CTNNA3
Structures
Search for
Structures	Swiss-model
Domains	InterPro

CTNNA3
Identifiers
Aliases	CTNNA3, ARVD13, VR22, catenin alpha 3
External IDs	OMIM: 607667; MGI: 2661445; HomoloGene: 56583; GeneCards: CTNNA3; OMA:CTNNA3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	67,763,637 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	64,839,446 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; right ventricle; ; internal globus pallidus; ; Skeletal muscle tissue of biceps brachii; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; external globus pallidus; ; pars reticulata; ; endothelial cell; ; pons;
	Top expressed in
	interventricular septum; ; seminiferous tubule; ; spermatid; ; lumbar subsegment of spinal cord; ; zygote; ; spermatocyte; ; muscle of thigh; ; primary oocyte; ; ventricle of the heart; ; left ventricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin filament binding; beta-catenin binding; protein binding; cadherin binding;
Cellular component	cytoplasm; adherens junction; fascia adherens; cytoskeleton; lamellipodium;
Biological process	cell adhesion; bundle of His cell-Purkinje myocyte adhesion involved in cell communication; regulation of heart rate by cardiac conduction; regulation of ventricular cardiac muscle cell action potential; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	29119
	216033
	ENSG00000183230
	ENSMUSG00000060843
	Q9UI47; Q8WW10
	Q65CL1
	NM_001127384; NM_001291133; NM_013266
	NM_001164376; NM_001164519; NM_177612
	NP_001120856; NP_001278062; NP_037398; NP_001120856.1; NP_001278062.1
	NP_001157848; NP_001157991; NP_808280
	Wikidata
View/Edit Human	View/Edit Mouse

Catenin alpha-3, also known as αT-catenin, is a α-catenin protein that in humans is encoded by the CTNNA3 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000183230 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060843 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Janssens B, Goossens S, Staes K, Gilbert B, van Hengel J, Colpaert C, Bruyneel E, Mareel M, van Roy F (September 2001). "alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion". J Cell Sci. 114 (17): 3177–88. doi:10.1242/jcs.114.17.3177. PMID 11590244.
↑ "Entrez Gene: CTNNA3, catenin alpha 3".

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000183230 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060843 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid_11590244-5] Janssens B, Goossens S, Staes K, Gilbert B, van Hengel J, Colpaert C, Bruyneel E, Mareel M, van Roy F (September 2001). "alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion". J Cell Sci. 114 (17): 3177–88. doi:10.1242/jcs.114.17.3177. PMID 11590244.

[entrez-6] "Entrez Gene: CTNNA3, catenin alpha 3".

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References