5-Hydroxyhydantoin

5-Hydroxyhydantoin
Names
	IUPAC name 5-Hydroxy-2,4-imidazolidinedione
	Other names Glyoxalurea; Allanturic acid
Identifiers
CAS Number	29410-13-7;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:195336;
ChemSpider	3369395;
PubChem CID	4157426;
UNII	53RWX86RYV ;
CompTox Dashboard (EPA)	DTXSID80400049 ;
	InChI InChI=1S/C3H4N2O3/c6-1-2(7)5-3(8)4-1/h1,6H,(H2,4,5,7,8) Key: WYLUZALOENCNQU-UHFFFAOYSA-N; InChI=1S/C3H4N2O3/c6-1-2(7)5-3(8)4-1/h1,6H,(H2,4,5,7,8) Key: WYLUZALOENCNQU-UHFFFAOYSA-N;
	SMILES OC1NC(=O)NC1=O;
Properties
Chemical formula	C3H4N2O3
Molar mass	116.076 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

5-Hydroxyhydantoin is an oxidation product of 2′-deoxycytidine. If not repaired, it may be processed by DNA polymerases that induce mutagenic processes.^[1]

References

↑ Gasparutto, Didier; Muller, Evelyne; Boiteux, Serge; Cadet, Jean (January 2009). "Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (1): 16–24. doi:10.1016/j.bbagen.2008.10.001. PMID 18983898.

[MyUser_Sciencedirect.com_August_5_2015c-1] Gasparutto, Didier; Muller, Evelyne; Boiteux, Serge; Cadet, Jean (January 2009). "Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases". Biochimica et Biophysica Acta (BBA) - General Subjects. 1790 (1): 16–24. doi:10.1016/j.bbagen.2008.10.001. PMID 18983898.

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References