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Cantharidic acid

From Wikipedia, the free encyclopedia
(Redirected from C10H14O5)
Cantharidic acid
Clinical data
ATC code
  • none
Identifiers
  • 2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard100.164.462 Edit this at Wikidata
Chemical and physical data
FormulaC10H14O5
Molar mass214.217 g·mol−1
3D model (JSmol)
  • CC1(C2CCC(C1(C)C(=O)O)O2)C(=O)O
  • InChI=1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)
  • Key:NMTNUQBORQILRK-UHFFFAOYSA-N

Cantharidic acid is a selective inhibitor of PP2A (protein phosphatase 2) and PP1 (protein phosphatase 1).[1][2]

It is the hydrolysis product of cantharidin.

See also

[edit]

References

[edit]
  1. "Cantharidic Acid | CAS 28874-45-5".
  2. Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A (August 2017). "The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse". Science Signaling. 10 (491) eaal2880. doi:10.1126/scisignal.aal2880. PMC 9437928. PMID 28790195. S2CID 4886031.