// Workers AI · dad joke modeWhat did SAMD4B say to its friend? Byte to meet you.

SAMD4B
Identifiers
Aliases	SAMD4B, SMGB, hSmaug2, Smaug2, sterile alpha motif domain containing 4B
External IDs	MGI: 2448542; GeneCards: SAMD4B
Gene location (Human)
Chr.	Chromosome 19 (human)
End	39,385,710 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	28,297,569 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; tibial nerve; ; C1 segment; ; right frontal lobe; ; ectocervix; ; gastric mucosa; ; left ovary; ; canal of the cervix; ; right ovary; ; anterior cingulate cortex;
	Top expressed in
	genital tubercle; ; tail of embryo; ; gastrula; ; granulocyte; ; lip; ; perirhinal cortex; ; zygote; ; yolk sac; ; right ventricle; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	mRNA binding; translation repressor activity; RNA binding;
Cellular component	nucleus; P-body; cytoplasm; cytosol;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; nuclear-transcribed mRNA poly(A) tail shortening; regulation of mRNA stability; negative regulation of translation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55095
	233033
	ENSG00000179134
	ENSMUSG00000109336
	Q5PRF9
	Q80XS6
	NM_001303614; NM_018028
	NM_175021
	NP_001290543; NP_060498
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Sterile alpha motif domain containing 4B is a protein that in humans is encoded by the SAMD4B gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000179134 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000109336 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Sterile alpha motif domain containing 4B". Retrieved 2020-04-16.

Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X (May 2010). "SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity". BMB Rep. 43 (5): 355–61. doi:10.5483/bmbrep.2010.43.5.355. PMID 20510020.

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