// Workers AI · dad joke modeWhy KLF16? It's a factor that binds.

KLF16
Identifiers
Aliases	KLF16, BTEB4, DRRF, NSLP2, Kruppel-like factor 16, Kruppel like factor 16
External IDs	OMIM: 606139; MGI: 2153049; GeneCards: KLF16
Gene location (Human)
Chr.	Chromosome 19 (human)
End	1,863,579 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,413,155 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; putamen; ; caudate nucleus; ; granulocyte; ; cingulate gyrus; ; anterior cingulate cortex; ; amygdala; ; monocyte; ; right frontal lobe; ; prefrontal cortex;
	Top expressed in
	zygote; ; superior frontal gyrus; ; visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; cumulus cell; ; secondary oocyte; ; primary visual cortex; ; epiblast; ; primary oocyte; ; female urethra;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription by RNA polymerase II; dopamine receptor signaling pathway; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	83855
	118445
	ENSG00000129911
	ENSMUSG00000035397
	Q9BXK1
	P58334
	NM_031918
	NM_078477
	NP_114124
	NP_510962
	Wikidata
View/Edit Human	View/Edit Mouse

Kruppel like factor 16 is a protein that in humans is encoded by the KLF16 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000129911 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035397 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Kruppel like factor 16". Retrieved 2018-07-09.

Kaczynski JA, Conley AA, Fernandez Zapico M, Delgado SM, Zhang JS, Urrutia R (September 2002). "Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter". Biochem. J. 366 (Pt 3): 873–82. doi:10.1042/BJ20020388. PMC 1222816. PMID 12036432.
Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S (July 2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes". Diabetologia. 48 (7): 1315–22. doi:10.1007/s00125-005-1797-0. PMID 15937668.
Gutiérrez-Aguilar R, Benmezroua Y, Vaillant E, Balkau B, Marre M, Charpentier G, Sladek R, Froguel P, Neve B (August 2007). "Analysis of KLF transcription factor family gene variants in type 2 diabetes". BMC Med. Genet. 8 53. doi:10.1186/1471-2350-8-53. PMC 1994949. PMID 17688680.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000129911 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035397 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Kruppel like factor 16". Retrieved 2018-07-09.

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References

Further reading