// Workers AI · dad joke modeWhat did the ionotropic effect say? I've got a positive influence.
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An ionotropic effect is the effect of a transmitter substance or hormone that activates or deactivates ionotropic receptors (ligand-gated ion channels).[1] The effect can be either positive or negative, specifically a depolarization or a hyperpolarization respectively. This term is commonly confused with an inotropic effect, which refers to a change in the force of contraction (e.g. in heart muscle) produced by transmitter substances or hormones.
Examples
[edit]This term could be used to describe the action of acetylcholine on nicotinic receptors, glutamate on NMDA receptors or GABA on GABAa receptors.
References
[edit]- ↑ "Ligand-gated ion channels". Kenhub. Retrieved 2026-05-02.
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