// Workers AI · dad joke modeWhat did DNAJC13 say to its friend? "Gene"uinely happy to see you.

DNAJC13
Identifiers
Aliases	DNAJC13, RME8, PARK21, DnaJ heat shock protein family (Hsp40) member C13
External IDs	OMIM: 614334; MGI: 2676368; HomoloGene: 13574; GeneCards: DNAJC13; OMA:DNAJC13 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3q22.1 Start 132,417,502 bp End 132,539,032 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 F1 Start 104,028,481 bp End 104,140,129 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon buccal mucosa cell saphenous vein trabecular bone superficial temporal artery parietal pleura trigeminal ganglion epithelium of nasopharynx tail of epididymis tibia Top expressed in zygote secondary oocyte genital tubercle tail of embryo cumulus cell saccule otic placode stroma of bone marrow human kidney primary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component lysosomal membrane endosome WASH complex early endosome membrane endosome membrane extracellular exosome early endosome membrane intracellular membrane-bounded organelle cytosol plasma membrane secretory granule membrane azurophil granule membrane Biological process protein transport regulation of early endosome to late endosome transport regulation of early endosome to recycling endosome transport osteoblast differentiation endosome organization neutrophil degranulation receptor-mediated endocytosis transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23317 235567 Ensembl ENSG00000138246 ENSMUSG00000032560 UniProt O75165 n/a RefSeq (mRNA) NM_015268 NM_001329126 NM_173823 NM_001163026 NM_001359740 RefSeq (protein) NP_001316055 NP_056083 n/a Location (UCSC) Chr 3: 132.42 – 132.54 Mb Chr 9: 104.03 – 104.14 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

DnaJ (Hsp40) homolog, subfamily C, member 13, also known as DNAJC13, is a human gene.

Further reading

• Girard M, Poupon V, Blondeau F, McPherson PS (2006). "The DnaJ-domain protein RME-8 functions in endosomal trafficking". J. Biol. Chem. 280 (48): 40135–43. doi:10.1074/jbc.M505036200. PMID 16179350.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Chang HC, Hull M, Mellman I (2004). "The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila". J. Cell Biol. 164 (7): 1055–64. doi:10.1083/jcb.200311084. PMC 2172058. PMID 15051737.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Volz A, Melkaoui R, Hildebrandt F, Omran H (2003). "Candidate gene analysis of KIAA0678 encoding a DnaJ-like protein for adolescent nephronophthisis and Senior-Løken syndrome type 3". Cytogenet. Genome Res. 97 (3–4): 163–6. doi:10.1159/000066617. PMID 12438707. S2CID 438753.
• Ishikawa K, Nagase T, Suyama M, et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.