// Workers AI · dad joke modeWhat did DDX59 say to its date? You're 59 times more lovely.

DDX59
Identifiers
Aliases	DDX59, OFD5, ZNHIT5, DEAD-box helicase 59
External IDs	OMIM: 615464; MGI: 1915247; GeneCards: DDX59
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YQP
Enzyme activity EC # BRENDA ExPASy KEGG MetaCyc 3.6.4.13 ↗ ↗ ↗ ↗
Gene location (Human) Chr. Chromosome 1 (human) Band 1q32.1 Start 200,623,896 bp End 200,669,907 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 E4 Start 136,343,009 bp End 136,367,896 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell pancreatic ductal cell tendon of biceps brachii oocyte secondary oocyte cardia endothelial cell mucosa of paranasal sinus renal medulla nipple Top expressed in saccule ectoderm otic vesicle otic placode secondary oocyte molar medullary collecting duct zygote interventricular septum muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding hydrolase activity ATP binding helicase activity metal ion binding RNA binding nucleic acid binding Cellular component intracellular anatomical structure nucleus nucleolus cytoplasm membrane integral component of membrane Biological process RNA secondary structure unwinding Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 83479 67997 Ensembl ENSG00000118197 ENSMUSG00000026404 UniProt Q5T1V6 Q5T1W1 Q9DBN9 RefSeq (mRNA) NM_001031725 NM_031306 NM_001320181 NM_001320182 NM_001349799 NM_001349800 NM_001349801 NM_001349802 NM_001349803 NM_001349804 NM_026500 NM_178052 RefSeq (protein) NP_001026895 NP_001307110 NP_001307111 NP_001336728 NP_001336729 NP_001336730 NP_001336731 NP_001336732 NP_001336733 NP_080776 Location (UCSC) Chr 1: 200.62 – 200.67 Mb Chr 1: 136.34 – 136.37 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Probable ATP-dependent RNA helicase DDX59 is an enzyme that in humans is encoded by the DDX59 gene.

Further reading

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.