Craig plot
 | This article relies on a single source. (January 2024) |
The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design.[1]
Two most used forms of a Craig plot are
- plotting the sigma constants of the Hammett equation versus hydrophobicity
- plotting the steric terms of the Taft equation against hydrophobicity
See also
[edit]References
[edit]- ↑ "IUPAC glossary". Archived from the original on 2006-12-09. Retrieved 2006-12-14.
Further reading
[edit]- Craig, Paul N. (1971). "Interdependence between physical parameters and selection of substituent groups for correlation studies". Journal of Medicinal Chemistry. 14 (8): 680–684. doi:10.1021/jm00290a004. PMID 5114063.
 | This article about medicinal chemistry is a stub. You can help Wikipedia by adding missing information. |