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Ananain

From Wikipedia, the free encyclopedia
Ananain
Identifiers
EC no.3.4.22.31
CAS no.119129-70-3
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Ananain (EC 3.4.22.31, stem bromelain, fruit bromelain) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Best reported small molecule substrate Bz-Phe-Val-Arg-NHMec

This enzyme is isolated from stem of pineapple plant, Ananas comosus.

References

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  1. Rowan AD, Buttle DJ, Barrett AJ (November 1988). "Ananain: a novel cysteine proteinase found in pineapple stem". Archives of Biochemistry and Biophysics. 267 (1): 262–70. doi:10.1016/0003-9861(88)90031-8. PMID 3196029.
  2. Rowan AD, Buttle DJ, Barrett AJ (March 1990). "The cysteine proteinases of the pineapple plant". The Biochemical Journal. 266 (3): 869–75. PMC 1131219. PMID 2327970.
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