Alistipes communis
| Alistipes communis | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Bacteroidota |
| Class: | Bacteroidia |
| Order: | Bacteroidales |
| Family: | Rikenellaceae |
| Genus: | Alistipes |
| Species: | A. communis |
| Binomial name | |
| Alistipes communis Sakamoto et al. 2020 | |
Alistipes communis is a rod or coccobacilli shaped, gram stain negative bacteria belonging to the family Rikenellaceae. Commonly found in the human gut microbiome, it is non-spore forming and has a size of about 0.8x1.7μm. This species was first discovered in 2020, where scientists took faecal samples from humans in Tsukuba, Ibaraki in Japan. 16S rRNA gene sequencing was used to sequence the genes.[1]
Morphology and physiology
[edit]These are some of the features of this species:[1]
- Optimum temperature for growth is 37°C but has a range of 25-37°C.
- Optimum pH of 7 with a range between pH 6.3-7.8.
- Metabolic process is glucose fermentation.
- This species can be grown on EG agar plates, with a medium composition of 20% bile.
Health
[edit]A 2024 study investigated changes to human gut microbiome in relation to intense effort exercise and found A. communis to be abundant in individuals undertaking strength training during the Wingate test (a test involving resistance cycling).[2]
A. communis was associated with favourable outcomes for melanoma treatment in a 2025 study where this species was enriched in long term survival patients after Fecal Microbiota Transplantation as a form of Immune Checkpoint Inhibitor therapy.[3]
Chickens
[edit]In 2026 a study from the Northeast Agricultural University in Harbin, China, conducted the first study of how A. communis mechanically contributed to its host.[4] The host species was chickens. Sixty-six chicks were involved in a study investigating A. communis and the regulation of abdominal fat percentage (AFD)[4]. When A. communis was introduced to the cecum (a pouch found at the start of the large intestine) of the chickens it caused shifts in the microbial cecum biome[4]. A. communis was found to be involved in the metabolism of amino acid, galactose, vitamins, amino/nucleotide sugars and carbon[4]. It was a key microbial species in regulating AFD in chickens, associated with an increase in the AFD, due to enhanced amino acid and carbohydrate metabolism[4].
References
[edit]- 1 2 Sakamoto, Mitsuo; Ikeyama, Nao; Ogata, Yusuke; Suda, Wataru; Iino, Takao; Hattori, Masahira; Ohkuma, Moriya (January 1, 2020). "Alistipes communis sp. nov., Alistipes dispar sp. nov. and Alistipes onderdonkii subsp. vulgaris subsp. nov., isolated from human faeces, and creation of Alistipes onderdonkii subsp. onderdonkii subsp. nov". International Journal of Systematic and Evolutionary Microbiology. 70 (1): 473–480. doi:10.1099/ijsem.0.003778. ISSN 1466-5026. PMID 31633480. Retrieved June 24, 2026.
- ↑ Humińska-Lisowska, Kinga; Zielińska, Kinga; Mieszkowski, Jan; Michałowska-Sawczyn, Monika; Cięszczyk, Paweł; Łabaj, Paweł P.; Wasąg, Bartosz; Frączek, Barbara; Grzywacz, Anna; Kochanowicz, Andrzej; Kosciolek, Tomasz (2024-02-21). "Microbiome features associated with performance measures in athletic and non-athletic individuals: A case-control study". PLOS ONE. 19 (2) e0297858. Bibcode:2024PLoSO..1997858H. doi:10.1371/journal.pone.0297858. ISSN 1932-6203. PMC 10880968. PMID 38381714.
- ↑ Hadi, Danial Khan; Baines, Kelly J; Jabbarizadeh, Behnam; Miller, Wilson H; Jamal, Rahima; Ernst, Scott; Logan, Diane; Belanger, Karl; Esfahani, Khashayar; Elkrief, Arielle; Parvathy, Seema Nair; Silverman, Michael S; Routy, Bertrand; Maleki Vareki, Saman; Lenehan, John Gordon (August 2025). "Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial". Journal for ImmunoTherapy of Cancer. 13 (8) e012659. doi:10.1136/jitc-2025-012659. ISSN 2051-1426. PMC 12359429. PMID 40759441.
- 1 2 3 4 5 Jing, Yang; Liu, Shuai; Leng, Li; He, Jiarui; Wang, Tianqi; Guan, Yunnan; Su, Zhiyong; Zhang, Wenpeng; Li, Yumao; Luan, Peng; Cheng, Bohan; Wang, Ning; Li, Hui (2026-05-20). "Microbiota transplantation and multi-omics profiling integration unveil the mechanism of Alistipes communis-driven abdominal fat deposition in chickens". Journal of Animal Science and Biotechnology. 17 (1): 98. doi:10.1186/s40104-026-01439-2. ISSN 2049-1891. PMC 13188826. PMID 42157342.