Talk:Spindle checkpoint

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Latest comment: 9 years ago1 comment1 person in discussion

Would this article^[1] be useful and appropriate to discuss in this article? If so, since it is from 2003, I wonder if there are any new studies that might shed more light on this concept?

References

↑ Cohen, Phillip (10 April 2003). "Human reproductive cloning 'currently impossible'". New Scientist. Reed Business Information. Retrieved 14 July 2017. On a hunch they examined the cells' spindles, structures that guide chromosomes into daughter cells as the embryo divides. The researchers found that SCNT primate embryos lacked at least two proteins required for proper spindle function, leaving the chromosomes to distribute randomly throughout the embryo. These proteins turn out to be tightly linked to the chromosomes in the monkey's eggs, which are removed in one of the first steps of the nuclear transfer process. Further, unpublished work by Schatten's group and others has shown the same is true for human cells. In contrast, mice and cows have extra copies of these proteins floating around to help out the cloned embryo. Schatten jokes: 'It's almost like God in her wisdom said go ahead and clone cows and sheep, but if you clone a human I'm going to paralyse the egg.' ... Journal reference: Science (vol 300, p 297).

Thanks to anyone who can look into this! —Geekdiva (talk) 03:32, 14 July 2017 (UTC)Reply

[1] Cohen, Phillip (10 April 2003). "Human reproductive cloning 'currently impossible'". New Scientist. Reed Business Information. Retrieved 14 July 2017. On a hunch they examined the cells' spindles, structures that guide chromosomes into daughter cells as the embryo divides. The researchers found that SCNT primate embryos lacked at least two proteins required for proper spindle function, leaving the chromosomes to distribute randomly throughout the embryo. These proteins turn out to be tightly linked to the chromosomes in the monkey's eggs, which are removed in one of the first steps of the nuclear transfer process. Further, unpublished work by Schatten's group and others has shown the same is true for human cells. In contrast, mice and cows have extra copies of these proteins floating around to help out the cloned embryo. Schatten jokes: 'It's almost like God in her wisdom said go ahead and clone cows and sheep, but if you clone a human I'm going to paralyse the egg.' ... Journal reference: Science (vol 300, p 297).

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Talk:Spindle checkpoint

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