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Talk:Safingol

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Latest comment: 11 months ago by CheckNineEight in topic Why is Dihydrosphingosine redirected to here?

Help with citations

[edit]

Can someone help with the references please? I think the infobox ref tag is messing the in-text citations up for some reason. I did them all the same way and the way I have done them in other articles, so not sure what's wrong. Thanks. PPSE15 (talk) 01:28, 30 May 2015 (UTC)Reply

Why is Dihydrosphingosine redirected to here?

[edit]
Resolved

Dihydrosphingosine and Safingol are different molecules.

Dihydrosphingosine, also known as Sphinganine.
Safingol. Notice how the hydroxy and amino groups are on the same chirality (OH is also on solid triangle like NH2) – unlike sphinganine, whose groups are on opposite chiralities (OH on "signal bars" instead of sold triangle). If the outermost OH were the "head" , then the solid triangle parts would be the "left hand"; safingol has two left-hand parts, whereas sphinganine has a left-hand and a right-hand part.

CheckNineEight (talk) 04:26, 27 June 2025 (UTC)Reply

"(−)-threo-Dihydrosphingosine" is listed as a synonym for safingol, so there is a partial match there. It is at least plausible that someone searching the text "dihydrosphingosine" is interested in safingol. However, it certainly may lead to confusion in other cases. The best solution would be to convert the redirect at Dihydrosphingosine into an article and note the similarity/relationship between the two in each article. Marbletan (talk) 18:36, 19 August 2025 (UTC)Reply
Maybe "Dihydrosphingosine" is an umbrella name for both Sphinganine and Safingol? Maybe we should keep Dihydrosphingosine a redirect page that links to both Safingol and Sphinganine (which is another page redirecting to safingol for some reason)? I don't know what's going on here. CheckNineEight (talk) 02:08, 20 August 2025 (UTC)Reply
That sounds perfectly reasonable to me. Sphinganine does appear to be the more common name for that other chemical compound and dihydrosphingosine is apparently an ambiguous term. I've gone ahead created a stub at sphinganine and a disambig page at dihydrosphingosine. Marbletan (talk) 12:55, 20 August 2025 (UTC)Reply
Did I make this chembox correctly?
Sphinganine
Names
IUPAC name
Sphinganine
Preferred IUPAC name
Sphinganine
Systematic IUPAC name
(2S,3R)-2-aminooctadecane-1,3-diol
Other names
  • Dihydrospingosine
  • DL-erythro-Dihydrosphingosine
  • 2-Amino-1,3-dihydroxyoctadecane
  • [R-(R*,S*)]-2-aminooctadecane-1,3-diol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
EC Number
  • 212-116-0
KEGG
UNII
  • InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
    Key: OTKJDMGTUTTYMP-ZWKOTPCHSA-N
  • C(CCCCCCCCCCCCCC)[C@H]([C@H](CO)N)O
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

CheckNineEight (talk) 08:17, 20 August 2025 (UTC)Reply

Looks good, I've incorporated it into sphinganine. Marbletan (talk) 12:55, 20 August 2025 (UTC)Reply
Nice. Nice. (Two times, the second one for the other reply above.) CheckNineEight (talk) 16:06, 20 August 2025 (UTC)Reply