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Surhone, L. M., Timpledon, M. T., & Marseken, S. F. (2010), Protein methods: Protein, Site-Directed Mutagenesis, Genetic Code, Green fluorescent Protein, His-Tag, BLAST, Genetic Linkage, Betascript Publishing{{citation}}: CS1 maint: multiple names: authors list (link)
Latest comment: 1 year ago1 comment1 person in discussion
Really nice article, with suitable coverage. The following points might be considered even if this article is granted FA status.
Lede paragraphs need to cite some big-time biochem textbooks.
For me, the tie-in to nutrition is not very relevant to understanding proteins. That section then goes on about essential amino acids, which is very tangential topic. Instead, this section should focus on digestion, which is a core aspect of proteins, how are they broken down? Peptidases. Industry conducts large scale hydrolyses to make some amino acids.
Could not understand this phrase: “As interactions between proteins are reversible and depend heavily on the availability of different groups of partner proteins to form aggregates that are capable to carry out discrete sets of ..”
A few places refer to “researchers” (which makes researchers seem like a caste-system). Usually such phrases can be recast to remove the term “researcher”
Heavy use of “key”. If nature uses something, it is key. So, often “key” is superfluous.
Heavy use of amino acid residues. Possibly somewhere the distinction between aa’s and their residues should be mentioned.
Prosthetic groups/cofactors are barely mentioned (or I missed it). My sense is that most proteins have these components (like the image of myoglobin).
The abundances of proteins could be mentioned. It is often stated that RuBisCO is an abundant protein because it is so inefficient as a protein. Anyway some sense of the protein inventories of various cells.
Health: are proteins used as vaccines or medicines.
Expected a reference to pryon/prion and self replication. It was not there, yet some articles link to Protein as kernels of self replication (along with RNA and DNA)
77.160.37.24 (talk) 17:38, 26 June 2025 (UTC)Reply
level-3 vital article is rated GA-class on Wikipedia's content assessment scale.
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