Talk:Phenacetin
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Metabolites
[edit]propyphenazone is NOT a metabolite of phenacetine!
- Exactly. Paracetamol is, propyphenazone not. I thus change the sentence.--84.163.119.98 01:40, 29 July 2007 (UTC)
Phenacetin an NSAID?
[edit]Phenacetin was not the first NSAID, because phenacetin is not an NSAID at all. It is an antipyretic analgesic, much like paracetamol/acetaminophen. NSAIDs are Non-Steroidal Anti-Inflammatory Drugs, thus they must have a primar antiinflammatory effect. Phenacetine, paracetamol and phenazone derivatives don't, although they are frequently incorrectly merged together with NSAIDs; these are antipyretic analgesics. The first NSAID used was sodium salicylate, followed by Aspirin.--84.163.119.98 01:46, 29 July 2007 (UTC)
Alzheimer's Disease
[edit]According to a NIH-published study, this drug may have caused the Alzheimer epidemic: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921468/ --X883 (talk) 23:15, 4 December 2015 (UTC)
References
[edit]Reference 1 is completely unrelated to the article??? — Preceding unsigned comment added by Starreactor (talk • contribs) 00:01, 30 November 2022 (UTC)
First synthesis
[edit]Who synthesized it first?
The article claims phenacetine was produced by Bayer in 1887, but also Harmon Northrop Morse reported the first synthesis in 1888. German wikipedia cites Oscar Hinsberg as the first to synthesized phenacetine. It appears that Morse synthesized paracetamol, not phenacetine. 2003:D1:2711:D700:91B4:D823:9285:2A0D (talk) 17:43, 24 September 2025 (UTC)