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Talk:NNK

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Latest comment: 2 years ago by Lumberjane Lilly in topic Cleanup needed in "Signaling pathways" subsection

there should be a category that would connect all 2,000 + known chemicals in cigarette smoke.

In the Metabolism paragraph appears the phrase, "α-methylhydoxylation [sic] or by α-methylenehydroxylation". Is the first word a typo? I assume it's "α-methylhydroxylation" missing the "r" but I don't wish to edit this personally because I lack experience in this field.

Cleanup needed in "Signaling pathways" subsection

[edit]

The entire "Signaling pathways" subsection needs extensive work. There are multiple issues I can see, although I only know enough to know that something is wrong, but not enough to know how to fix it. I've cleaned up the copy/grammar errors and added a few internal links, but this will definitely need attention from an expert.

To start, I'm not sure what "μ en m-calpain kinase" is, and it's not clear from context. It also says that "NNK promotes cell survival via phosphorylation" but does not state what is being phosphorylated (NNK itself? Another molecule?). The sentence "When NNK is present it directly involves cellular survival dependent on NFκB." doesn't quite make grammatical sense to me and I can't figure out how to fix it.

Everything else seems reasonably okay, and I've cleaned up what I can, but this still needs attention. Lumberjane Lilly (talk) 15:16, 19 June 2024 (UTC)Reply