Talk:Metabolome

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Molecular Biology: MCB / COMPBIO

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Latest comment: 6 years ago1 comment1 person in discussion

To be considered to be part of the metabolome, a small molecule must typically have a molecular weight <1500 Da.^[1] This means that molecules such as glycolipids, polysaccharides, short peptides (<14 amino acids) and small oligonucleotides (<5 bases) can be regarded as metabolites or constituents of the metabolome. On the other hand, very large macromolecules such as proteins, messenger RNA, ribosomal RNA, microRNA and DNA are definitely not metabolites and are not considered to be part of the metabolome.

This definition is outdated and incorrect. It excludes metabolites such as some tannins and proanthocyanidins ^[2] that are >1500Da but are nonetheless metabolites. The context of the citation in the deleted text is about small molecules and not what constitutes metabolites. Molecules >1500Da can easily be detected by many methods. Veryhuman (talk) 17:50, 23 October 2019 (UTC)Reply

References

↑ Cite error: The named reference ref_17626065 was invoked but never defined (see the help page).
↑ Bate-Smith and Swain (1962). "Flavonoid compounds". In Florkin M.; Mason H. S (eds.). Comparative biochemistry. Vol. III. New York: Academic Press. pp. 75–809.

[ref_17626065-1] Cite error: The named reference ref_17626065 was invoked but never defined (see the help page).

[Bate-Smith-2] Bate-Smith and Swain (1962). "Flavonoid compounds". In Florkin M.; Mason H. S (eds.). Comparative biochemistry. Vol. III. New York: Academic Press. pp. 75–809.

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Talk:Metabolome

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