Talk:MEGAN

Untitled

CorenSearchBot is in error. This text was originally formulated by Daniel Huson for his website: www-ab.informatik.uni-tuebingen.de/software/megan and then used by others.

Issues

• 1) Can you please sign your comments with 4 tildes (~)
• 2) Notability probably needs to be properly asserted and referenced
• 3) Some attempt must be made to have this page be more than just an "advertisement".

I also almost marked it for Speedy Delete as Spam but, am WP:AGF for now. Jasynnash2 (talk) 10:23, 2 April 2008 (UTC)

From article, needs rewritten.

Most published studies employ the analysis of paired-end reads, complete sequences of environmental fosmid and BAC clones, or environmental assemblies. Emerging very-high-throughput sequencing technologies are paving the way to low-cost random shotgun approaches.

Assignment of Reads to Taxa

An LCA-based algorithm assigns reads to taxa in such a way that the taxonomical level of the assigned taxon reflects the level of conservation of the sampled sequence. The software allows dissection of large datasets without the need for assembly or the targeting of specific phylogenetic markers. It provides graphical and statistical output for the comparison of different data sets. We have sucessfully applied this approach to a number of datasets obtained by Sanger sequencing and sequencing-by-synthesis technology, including the Sargasso Sea dataset, a recently published metagenomic dataset sampled from a mammoth bone, and several complete microbial genomes.

Comparison and Analysis of Multiple Datasets

The most recent version of MEGAN allows comparative analyses of datasets.

COG analysis

MEGAN provides tools for analysing the functional content of a metagenome.

--Blechnic (talk) 03:19, 3 April 2008 (UTC)