Talk:Lupus

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Lupus.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

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Famous case

Latest comment: 1 year ago2 comments2 people in discussion

Assyrian king Esarhaddon is suspected to have suffered from Lupus by Finnish Assyriologist Simo Parpola.

Parpola, Simo: Letters from Assyrian Scholars to the Kings Esarhaddon and Assurbanipal, 2007, p.232. https://www.google.de/books/edition/Letters_from_Assyrian_Scholars_to_the_Ki/JimYncnzaOkC?hl=de&gbpv=1&dq=Parpola+%22esarhaddon+as+systemic+lupus%22&pg=PA232&printsec=frontcover 2001:1A81:5396:6500:4901:9698:929E:832E (talk) 23:35, 4 January 2024 (UTC)Reply

Esarhaddon^[who?]

Disregarding that, one author's random speculative diagnosis doesn't equal a "famous case" or even make it notable. A Shortfall Of Gravitas (talk) 03:23, 26 April 2025 (UTC)Reply

Semi-protected edit request on 9 December 2024

Latest comment: 1 year ago2 comments2 people in discussion

This edit request has been answered. Set the |answered= parameter to no to reactivate your request.

I suggest to add two sentences to the information under the "Sex" heading which is under "Epidemiology" for Lupus, which would speak to new research discoveries focused on age-associated B cells and their relation to the female bias in lupus. Here are the two sentences I suggest, including their citations:

Age-associated B cells, a type of B cell that typically increase as people age, proliferate at an earlier age in people with an autoimmune disease such as lupus.^[1] A study has shown the dysfunction of age-associated B cells may be a contributor to the female bias of lupus^[2] due to a gene on the X-chromosome that is also known to escape silencing by X-chromosome inactivation, TLR7.^[3] Brielle White (talk) 00:42, 9 December 2024 (UTC)Reply

Not done @Brielle White: Please change the citations to conform to Wikipedia's guidelines for citing sources. Then the edit can be made. P,TO 19104 (talk) (contribs) 02:57, 23 December 2024 (UTC)Reply

References

↑ Sachinidis, A., Xanthopoulos, K., & Garyfallos, A. (2020). Age-Associated B Cells (ABCs) in the Prognosis, Diagnosis and Therapy of Systemic Lupus Erythematosus (SLE). Mediterranean journal of rheumatology, 31(3), 311–318. https://doi.org/10.31138/mjr.31.3.311
↑ Ricker, E., Manni, M., Flores-Castro, D., Jenkins, D., Gupta, S., Rivera-Correa, J., Meng, W., Rosenfeld, A. M., Pannellini, T., Bachu, M., Chinenov, Y., Sculco, P. K., Jessberger, R., Prak, E. T., & Pernis, A. B. (2021). Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-25102-8
↑ Souyris, M., Cenac, C., Azar, P., Daviaud, D., Canivet, A., Grunenwald, S., Pienkowski, C., Chaumeil, J., Mejía, J. E., & Guéry, J. C. (2018). TLR7 escapes X chromosome inactivation in immune cells. Science immunology, 3(19), eaap8855. https://doi.org/10.1126/sciimmunol.aap8855

Semi-protected edit request on 5 November 2025

Latest comment: 8 months ago2 comments2 people in discussion

This edit request has been answered. Set the |answered= parameter to no to reactivate your request.

Add PubMed articles linking lupus with Trisomy X. https://pmc.ncbi.nlm.nih.gov/articles/PMC9295272/ and https://pubmed.ncbi.nlm.nih.gov/26713507/ would be fitting additions. BruceIsBest (talk) 23:07, 5 November 2025 (UTC)Reply

Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate.

Where do you want to add these? Please make your request clear and specific. Thank you in advance, you can ping me in your answer or reactivate the request (by changing the answered= parameter) once you have clarified.

PS: I removed what I assumed was a typo after your signature.

Happy editing. Slomo666 (talk) 01:10, 6 November 2025 (UTC)Reply

Semi-protected edit request 4 December 2025

Latest comment: 7 months ago2 comments2 people in discussion

Under "Treatment", second paragraph, third sentence. "Hydroxychloroquine" is misspelled as "hydroxychloroquiine". BarrenScepter (talk) 20:17, 4 December 2025 (UTC)Reply

Done Fixed. Ruslik_Zero 20:35, 4 December 2025 (UTC)Reply

Research Suggestion

Latest comment: 2 months ago1 comment1 person in discussion

I suggest adding information under the “Research” section or a “New drug possibilities” section about emerging work on Epstein–Barr virus (EBV) and lupus. Recent research suggests a potential mechanistic link between EBV infection and systemic lupus erythematosus. Several companies are developing EBV vaccines, and early clinical trials are underway. These vaccines would not treat existing lupus but may reduce the risk of initial EBV infection, which has been identified as a possible trigger contributing to lupus development. ^[1] Scilly892 (talk) 01:32, 12 May 2026 (UTC)Reply

↑ "Stanford Medicine scientists tie lupus to a virus nearly all of us carry". Stanford Medicine News Center. Stanford University. November 2025. Retrieved 11 May 2026.

[1] Sachinidis, A., Xanthopoulos, K., & Garyfallos, A. (2020). Age-Associated B Cells (ABCs) in the Prognosis, Diagnosis and Therapy of Systemic Lupus Erythematosus (SLE). Mediterranean journal of rheumatology, 31(3), 311–318. https://doi.org/10.31138/mjr.31.3.311

[2] Ricker, E., Manni, M., Flores-Castro, D., Jenkins, D., Gupta, S., Rivera-Correa, J., Meng, W., Rosenfeld, A. M., Pannellini, T., Bachu, M., Chinenov, Y., Sculco, P. K., Jessberger, R., Prak, E. T., & Pernis, A. B. (2021). Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-25102-8

[3] Souyris, M., Cenac, C., Azar, P., Daviaud, D., Canivet, A., Grunenwald, S., Pienkowski, C., Chaumeil, J., Mejía, J. E., & Guéry, J. C. (2018). TLR7 escapes X chromosome inactivation in immune cells. Science immunology, 3(19), eaap8855. https://doi.org/10.1126/sciimmunol.aap8855

[4] "Stanford Medicine scientists tie lupus to a virus nearly all of us carry". Stanford Medicine News Center. Stanford University. November 2025. Retrieved 11 May 2026.

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