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Talk:Hypercalcaemia

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Latest comment: 2 months ago by Catcus DeMeowwy in topic Causes

Causes

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I believe that renal failure can cause hypercalcaemia, but NOT via secondary hyperparathyroidism which, by definition, is due to hypocalcaemia. So-called tertiary hyperparathyroidism is a cause of hypercalcaemia, albeit a rare one.  Preceding unsigned comment added by 130.56.52.140 (talk) 06:54, 3 May 2015 (UTC)Reply

  1. Hypercalcemia causing kidney disease. [1] 2. hypocalcemia in CKD[2]
~ ~It's me, Catcus DeMeowwy (talk page) 21:54, 7 May 2026 (UTC)Reply

Symptoms

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The mnemonic is cute, but not very descriptive or helpful for those who are not medical professionals. For example, what is meant by "psychotic noise"? Is this a medical term? I'm having difficulty finding a definition. 24.34.190.157 (talk) 12:34, 4 November 2009 (UTC)Reply

I think it is mental disorders (psychic moans). ~ ~It's me, Catcus DeMeowwy (talk page) 15:26, 5 May 2026 (UTC)Reply

mnemonic is offensive, and unprofessional —Preceding unsigned comment added by 69.253.50.157 (talk) 07:50, 3 June 2010 (UTC)Reply

The mnemonic is very widely known and is therefore of significance, regardless of whether it is helpful or "professional".  Preceding unsigned comment added by 130.56.52.140 (talk) 06:57, 3 May 2015 (UTC)Reply

The technical term for "psychotic noise" is hearing voices
What's wrong with a mnemonic? The Great Unwashed might be able to understand something professional and encroach on your sacred territory? It worked for me. I'm not a health professional (my expertise lies elsewhere), but it was my understanding that Wikipedia was designed to be accessible to everyone -- including doctors, who are as prone to forgetfulness as anyone else. I stumbled across this excellent article in a hunt for causes of leg pain, and I didn't take an elevated calcium level seriously until I found this. I hear music most of the time, sometimes whole choruses of "voices" (along with harpsichords, Andean flutes, you name it) and I'm quite sane, thank you. I knew instantly what the writer was referring to. What would you call it? 24.4.28.149 (talk) 18:08, 4 July 2010 (UTC)Reply

?Nonsense

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Until someone can provide a reference to this I think it should be considered of dubious provenance Ianmc 19:34, 14 August 2007 (UTC) 'Differential diagnoses include pseudo-hypercalcemia (Meade syndrome) and hyper-hypercalcemia (Rozeaous syndrome)'Reply

Williams Syndrome

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Where does williams syndrome fit among causes of this symptom? I know it's genetic, but the hypercalcaemia might be secondary to another symptom of the syndrome.--Joel 23:00, 12 May 2005 (UTC)Reply

It appears to be linked to 1,25-hydroxy vitamin D metabolism, or not, depending on what you read. But as no one is quite sure why normal neonates have higher calcium levels than usual I don't think a consensus answer will be forthcoming from the literature Ianmc

Phaeo and hypercalaemia

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OK, I'm intrigued. How does a phaeo cause hypercalcaemia via increased bone turnover? Ianmc 16:42, 1 June 2006 (UTC)Reply

My mistake, it should be under malignancy for release of PTHrP. thanks for the quick catch! pretty of new at wiki here. User:koolkao Ming-Chih Kao 19:52, 1 June 2006 (UTC)Reply

Redirect is wrong

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There is a redirect from "Hypercalciuria" to "Hypercalcemia" - the two conditions are actually different, with hypercalciuria being a spilling of calcium in urine rather than blood. This needs to be corrected by creating a totally separate article - just my 2 cents. —The preceding unsigned comment was added by Virgil Vaduva (talkcontribs) 16:18, 16 February 2007 (UTC).Reply

Glad I read this and got scared. Recent redir (R to calcium deficiency) at hypocalcia (calcium deficiency), which I hope is correct. ~ ~It's me, Catcus DeMeowwy (talk page) 15:25, 5 May 2026 (UTC)Reply

Hypercalcaemia is the preferred spelling, not Hypercalcaemia. Article should be renamed.

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Hypercalcemia About 1,300,000 results Hypercalcaemia About 413,000

Denied. Please refer to WP:ENGVAR which explains why we don't Americanise all our title. JFW | T@lk 09:06, 24 December 2014 (UTC)Reply

PTH for diagnosis

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JAMA doi:10.1001/jama.2014.9195 JFW | T@lk 09:06, 24 December 2014 (UTC)Reply

PTH can be used for diagnosis as it is the cause (via primary hyperparathyroidism) in 90% of cases.[3][4] ~ ~It's me, Catcus DeMeowwy (talk page) 21:44, 7 May 2026 (UTC) ~ ~It's me, Catcus DeMeowwy (talk page) 21:44, 7 May 2026 (UTC)Reply

Hypercalcaemic crisis

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doi:10.1016/j.amjmed.2014.09.030 - review in Am J Med JFW | T@lk 22:06, 26 February 2015 (UTC)Reply

Vitamin K

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What about high-dose vitamin K, particularly vitamin K2, for preventing the problems associated with hypercalcaemia? --IO Device (talk) 22:25, 4 June 2015 (UTC)Reply

When vitamin D in involved

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doi:10.1210/er.2016-1070 JFW | T@lk 20:50, 4 September 2016 (UTC)Reply

[edit]
Hypercalcemia
Other names
<font-color:white>Stones, groans, and psychic moans</font-color>
, ;#/Hypercalcaemia[5][6]
SpecialtyEndocrinology
SymptomsAbdominal pain, bone pain, confusion, depression, weakness[7][8]
ComplicationsKidney stones, abnormal heart rhythm, cardiac arrest[7][8]
CausesPrimary hyperparathyroidism, cancer, sarcoidosis, tuberculosis, Paget disease, multiple endocrine neoplasia, vitamin D toxicity[7][9]
Diagnostic methodBlood serum level > 2.6 mmol/L (corrected calcium or ionized calcium)[7][8]
TreatmentUnderlying cause, intravenous fluids, furosemide, calcitonin, pamidronate, hemodialysis[7][8]
MedicationSee article
Frequency4 per 1,000[7]

}} Catcus DeMeowwy (talk) 21:37, 12 April 2026 (UTC)Reply

Infobox (frequency)

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The infobox on this page lists frequency of hypercalcemia as 4/1,000 people, and Google says the prevalence is 3% in hospitals. The number used in Hypocalcemia (in infobox) is higher, but I read in NIH NLM that hypercalcemia is more prevailant.[10] ~ ~It's me, Catcus DeMeowwy (talk page) 15:23, 5 May 2026 (UTC)Reply

I have changed the infobox (see topic below by me). ~ ~It's me, Catcus DeMeowwy (talk page) 21:41, 7 May 2026 (UTC)Reply

References

  1. Tinawi, Mohammad (2021-01-01). "Disorders of Calcium Metabolism: Hypocalcemia and Hypercalcemia". Cureus. 13 (1): e12420. doi:10.7759/cureus.12420. ISSN 2168-8184. PMC 7849212. PMID 33542868.{{cite journal}}: CS1 maint: article number as page number (link) CS1 maint: unflagged free DOI (link)
  2. Goyal, Abhinav; Anastasopoulou, Catherine; Ngu, Michael; Singh, Shikha (2026), "Hypocalcemia", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 28613662, retrieved 2026-05-07, CKD leads to impaired phosphate excretion and hydroxylation of 25 hydroxyvitamin D to 1,25-dihydroxy vitamin D. This drives PTH secretion and can cause secondary hyperparathyroidism. However, due to impaired vitamin D metabolism and high phosphorus levels, the serum calcium remains low despite the high PTH.
  3. Minisola, S.; Pepe, J.; Piemonte, S.; Cipriani, C. (2015-06-02). "The diagnosis and management of hypercalcaemia". BMJ. 350 (jun02 15): h2723–h2723. doi:10.1136/bmj.h2723. ISSN 1756-1833.
  4. Sadiq, Nazia M.; Anastasopoulou, Catherine; Patel, Goonja; Badireddy, Madhu (2026), "Hypercalcemia", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 28613465, retrieved 2026-05-07
  5. Cite error: The named reference MeSH descriptor was invoked but never defined (see the help page).
  6. Cite error: The named reference SNOMED was invoked but never defined (see the help page).
  7. 1 2 3 4 5 6 Cite error: The named reference BMJ2015 was invoked but never defined (see the help page).
  8. 1 2 3 4 Cite error: The named reference EU2010 was invoked but never defined (see the help page).
  9. Cite error: The named reference PMH2016 was invoked but never defined (see the help page).
  10. Goyal, Abhinav; Anastasopoulou, Catherine; Ngu, Michael; Singh, Shikha (2026), "Hypocalcemia", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 28613662, retrieved 2026-05-05, Though hypocalcemia is not encountered as frequently as hypercalcemia...

Prevalence (ref)

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Infobox states that hypercalcemia affects 1 in 1000 people (0.1% of people). I cannot find a mention of this in the ref (BMJ) used. This ref[1] states that it affects 1-4% (1 in 100) of the general population, but I understand that it might not follow Wikipedia's rules for refs. I made this talk page topic because of this and also so that the reference used in the infobox (I have edited the infobox) can be looked at by someone else. ~ ~It's me, Catcus DeMeowwy (talk page) 21:40, 7 May 2026 (UTC) ~ ~It's me, Catcus DeMeowwy (talk page) 21:40, 7 May 2026 (UTC)Reply

  1. Tinawi, Mohammad (2021-01-01). "Disorders of Calcium Metabolism: Hypocalcemia and Hypercalcemia". Cureus. doi:10.7759/cureus.12420. ISSN 2168-8184.{{cite journal}}: CS1 maint: unflagged free DOI (link)