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Talk:Epothilone

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Latest comment: 10 years ago by Anypodetos in topic Definition

Which are naturally found - is it all of A - F

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Which are naturally found - is it all of A - F ? Are all the synthetic ones referred to as analogs ? - Rod57 (talk) 11:55, 13 June 2016 (UTC)Reply

Yes, A to F are natural compounds ("As of September 2008, epothilones A to F have been identified and characterised."). --ἀνυπόδητος (talk) 19:52, 13 June 2016 (UTC)Reply

Definition

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What is the definition of an epothilone ? Is it the 16-member macrolide ring with a thiazole/olefin side-chain , or something more specific (just the 6 configurations A-F (of the 8 possible combinations of 2 thiazole side chains with 4 ring structures)) ? - Rod57 (talk) 12:12, 13 June 2016 (UTC)Reply

I don't think there is a convention about what an epothilone and what an epothilone analogue is. There aren't even any substances on the market yet. (For example, no one refers to azithromycin as a "macrolide analog" although it doesn't really meet the original definition of "macrolide" and isn't found in nature.) --ἀνυπόδητος (talk) 19:52, 13 June 2016 (UTC)Reply