Talk:Bromocriptine

I think this page is miscategorized. Hypogonadism is not "feminism-related" or "Female-related".

I agree. Men can suffer with pituitary disease and Parkinson's disease.

I added the information related to cocaine abuse. Although mitigation of cocaine addiction is not a current indication for bromocriptine I felt it very relevant to the page and added some links referring to the ongoing research in that area. --BroodGimp 20:49, 14 January 2006 (UTC)

You'd benefit from high D3 affinity and lower D2 affinity for this, however the Emax's should be >80% for both. Vraylar would work if Emax's were not taken into account.

-___)(_*()_*_(*_())(_)( 159.123.253.1 (talk) 15:28, 6 July 2025 (UTC)

Feel free to erase my comment, if it's not supposed to go here. Do medication articles list if it's over the counter or prescription in most countries?

Irreversible dopaminergic agonist?

It's mentioned as a functionally irreversible agonist, but maybe has something to do with covalent bonding like oxymorphazone does for the mu-receptor only on the dopamine system?

"The ability of the dopamine receptor antagonist spiperone [749-02-0] to block dopamine [51-61-6]- or bromocriptine (I) [25614-03-3]- inhibited prolactin [9002-62-4] release from dispersed rap anterior pituitary cells was tested in vitro. In a continuously perfused cell column app., spiperone rapidly counteracted the inhibitory effect of dopamine but was unable to reverse the inhibitory effect of I when added 30 min after I. However, spiperone completely blocked the action of I if added simultaneously with I. These basic data were confirmed, and the time relations more accurately defined, in static incubations of monolayer culture. Spiperone blocked the typical inhibition of prolactin release by I only if the cells were pre- or coincubated with the antagonist. If spiperone was added as soon as 1 min after I, the antagonist was unable to block the complete expression of the I inhibition. Evidently, I is a functionally irreversible dopamine agonist for at least the 4 h of these studies." source: European Journal of Pharmacology 1984, 99(1), p.85 Nagelfar (talk) 19:03, 20 October 2008 (UTC)

Doesn't exist yet. The doses in the petri dish may have had been different due to purity issues and miscalculation in mols used

-_-__)()(*()**( 159.123.253.1 (talk) 15:27, 6 July 2025 (UTC)

Subtle Vandalism?

"two peptide groups of its tripeptide moiety (shown in black at the upper left of the Figure) are crosslinked with Meagan Haases, forming the >N-C(OH)< juncture between the two rings with the amide functionality"

I'm not sure who or what Meagan Haases is but I'm fairly confident it has nothing to do with peptide linkages. I don't know enough about this class of compounds to be able to change that into something appropriate. 174.23.200.137 (talk) 14:30, 19 June 2010 (UTC)

External links modified

Hello fellow Wikipedians,

I have just modified 2 external links on Bromocriptine. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20131108013656/http://pdsp.med.unc.edu/pdsp.php to http://pdsp.med.unc.edu/pdsp.php
• Added archive https://web.archive.org/web/20090822125308/http://www.acromegalycommunity.com:80/content/pages/acromegaly-drug-info to http://www.acromegalycommunity.com/content/pages/acromegaly-drug-info

When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at {{Sourcecheck}}).

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 06:44, 9 November 2016 (UTC)

bromocriptine

drug — Preceding unsigned comment added by 156.203.158.112 (talk) 18:15, 6 April 2019 (UTC)

Wrong Emax? -_-_____(*)(*&)(

Beta-Arrestin recruitment makes more sense for the Dopamine D2 receptor activation since it has successfuly restored movement after collapsing after Haloperidol 400mg and only 26mg was used to completely override it.

-_-_____ 159.123.253.1 (talk) 15:07, 6 July 2025 (UTC)