Talk:Biperiden
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Availability
[edit]This drug is discontinued manufactured in the U.S. I take it. I need it! Please find out if someone knows about if it will ever be made again. Thank you — Preceding unsigned comment added by 75.161.136.190 (talk)
receptors binding
[edit]Potent, selective M1 receptor antagonist (Ki values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M1, M4, M3, M2 and M5 receptors respectively). http://www.abcam.com/Biperiden-hydrochloride-ab141781.pdf https://www.scbt.com/scbt/product/biperiden-hydrochloride-1235-82-1 — Preceding unsigned comment added by 109.241.248.66 (talk) 15:30, 25 October 2014 (UTC)
Tourette syndrome treatment
[edit]Citation needed for biperiden's usage in treating Tourette syndrome.
All I could find was a case report of treating extrapyramidal symptoms caused by dopamine antagonists in a Tourette syndrome patient.
This one showed resolution of symptoms:
https://doi.org/10.1345/aph.1g331
I also found a case study of biperiden in a patient with schizophrenia and Tardive Tourette-like syndrome induced by antipsychotics, in which it appeared ineffective.
https://doi.org/10.1111/j.1440-1819.1992.tb00821.x
I could not find any source regarding the treatment of TS-proper with biperiden. Sappygang (talk) 12:33, 5 April 2024 (UTC)
Can anybody help clarify following
[edit]"Biperiden is no longer marketed in the United States." Is this statement correct? if so, the reason? Thank you for your kind attention. ThomasYehYeh (talk) 13:51, 5 May 2024 (UTC)