Talk:Beta blocker
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Cancer treatment potential
[edit]Well-designed, prospective, randomized controlled trials are essential to confirm the efficacy of beta-blockers in TNBC, identify optimal agents, dosages, and patient populations, however, since 2013 there were added quite a few sources researching which beta-blockers impact cancer and how: https://pubmed.ncbi.nlm.nih.gov/22819786/
https://pubmed.ncbi.nlm.nih.gov/26745035/ Breast Cancer - Review, highly trusted source
https://pmc.ncbi.nlm.nih.gov/articles/PMC4869944/#sec12 TNBC in-vivo
May I add these? ~~~ Xobbitua (talk) 17:05, 27 May 2025 (UTC)
Carvedilol Edit Revision
[edit]Hey There @Just-a-can-of-beans:! I hope you’re doing well :P I noticed in this diff you removed “Carvedilol therapy is commonly associated with edema.[1][page needed]” as “I can find absolutely nothing to corroborate this statement that references an entire book nonspecifically, so I'm removing it”. That’s totally a sensible thing to do; it’s a shame the page sat there unsourced for so long before you were able to get to it.
That said, I am going to add it back in, this time with supporting sources, since it is a common side effect of all BB but notably more specific to carvedilol than other BB. This is due to carvedilol's dual mechanism of action as an alpha-1 blocker, which causes vascular smooth muscle relaxation. I’ve cited a drug review from NEJM [2] and a monograph from Meyler’s Side Effects of Drugs [3] but pretty much any medicines formulary/handbook like BNF, Micromedex, AMH, UpToDate LexiDrug, AHFS, etc., as well as the product information will have it listed as a side effect. Let me know if you have any issues at all with this; I’m always happy to discuss, and have a great day! 恋ren ｡☆ (talk) 07:49, 22 July 2026 (UTC)
Completed- I completed the edit mentioned above here: []
- If anyone has an qualms at all, please feel free to discuss! Have a fantastic day!
- 恋ren ｡☆ (talk) 08:24, 22 July 2026 (UTC)
- No issues at all, now that there's some proper reasoning and sources backing it. Thank you very much! Just-a-can-of-beans (talk) 20:18, 22 July 2026 (UTC)
- ↑ Cite error: The named reference
Rossiwas invoked but never defined (see the help page). - ↑ Frishman, William H. (1998). "Carvedilol". New England Journal of Medicine. 339 (24): 1759–1765. doi:10.1056/NEJM199812103392407. PMID 9845712.
- ↑ Aronson, J.K. (2016). "Carvedilol". In Aronson, J.K. (ed.). Meyler's Side Effects of Drugs (16th ed.). Elsevier. pp. 167–169. doi:10.1016/B978-0-444-53717-1.00460-1. ISBN 978-0-444-53717-1.