// Workers AI · dad joke modeWhat did TSFM say to its date? "You're a great frequency match

TSFM
Identifiers
Aliases	TSFM, EFTS, EFTSMT, Ts translation elongation factor, mitochondrial
External IDs	OMIM: 604723; MGI: 1913649; GeneCards: TSFM
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CP9
Gene location (Human) Chr. Chromosome 12 (human) Band 12q14.1 Start 57,782,761 bp End 57,808,071 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 D3 Start 126,847,441 bp End 126,866,709 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal gland left adrenal gland right adrenal cortex left adrenal cortex gonad skeletal muscle tissue gastrocnemius muscle islet of Langerhans left ventricle mucosa of transverse colon Top expressed in right kidney interventricular septum yolk sac embryo embryo proximal tubule stomach epiblast endocardial cushion hand More reference expression data BioGPS More reference expression data
Gene ontology Molecular function translation elongation factor activity RNA binding protein binding Cellular component mitochondrial matrix intracellular anatomical structure mitochondrion nucleus Biological process translational elongation regulation of DNA-templated transcription, elongation protein biosynthesis mitochondrial translational elongation regulation of mitochondrial translation Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 10102 66399 Ensembl ENSG00000123297 ENSMUSG00000040521 UniProt P43897 Q9CZR8 RefSeq (mRNA) NM_005726 NM_001172695 NM_001172696 NM_001172697 NM_025537 RefSeq (protein) NP_001166166 NP_001166167 NP_001166168 NP_005717 NP_079813 Location (UCSC) Chr 12: 57.78 – 57.81 Mb Chr 10: 126.85 – 126.87 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. It is an EF-Ts homolog.

Further reading

• Smeitink JA, Elpeleg O, Antonicka H, et al. (2006). "Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs". Am. J. Hum. Genet. 79 (5): 869–77. doi:10.1086/508434. PMC 1698578. PMID 17033963.
• Antonicka H, Sasarman F, Kennaway NG, Shoubridge EA (2006). "The molecular basis for tissue specificity of the oxidative phosphorylation deficiencies in patients with mutations in the mitochondrial translation factor EFG1". Hum. Mol. Genet. 15 (11): 1835–46. doi:10.1093/hmg/ddl106. PMID 16632485.
• Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika. 42 (2): 274–7. PMID 16583711.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Vernon JL, Burr PC, Wiley JE, Farwell MA (2000). "Assignment of the mitochondrial translation elongation factor Ts gene (TSFM) to human chromosome 12 bands q13→q14 by in situ hybridization and with somatic cell hybrids". Cytogenet. Cell Genet. 89 (3–4): 145–6. doi:10.1159/000015596. PMID 10965106. S2CID 201991811.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Benkowski LA, Takemoto C, Ott G, et al. (1996). "Interaction of mitochondrial elongation factors Tu.Ts with aminoacyl-tRNA". Nucleic Acids Symp. Ser. (33): 163–6. PMID 8643359.

External links

• TSFM human gene location in the UCSC Genome Browser.
• TSFM human gene details in the UCSC Genome Browser.