TRAPPC4

TRAPPC4
Identifiers
Aliases	TRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA, trafficking protein particle complex subunit 4
External IDs	OMIM: 610971; MGI: 1926211; HomoloGene: 105453; GeneCards: TRAPPC4; OMA:TRAPPC4 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2J3T, 2JSN, 2ZMV
Gene location (Human)
Chr.	Chromosome 11 (human)
End	119,025,454 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	44,318,897 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; anterior pituitary; ; right testis; ; left testis; ; stromal cell of endometrium; ; ganglionic eminence; ; right adrenal gland; ; left adrenal gland; ; left adrenal cortex; ; human kidney;
	Top expressed in
	medial ganglionic eminence; ; right kidney; ; ventricular zone; ; neural tube; ; morula; ; otic placode; ; granulocyte; ; facial motor nucleus; ; dentate gyrus of hippocampal formation granule cell; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytosol; Golgi apparatus; synaptic vesicle; synapse; dendrite; endoplasmic reticulum; Golgi stack; Golgi membrane; TRAPP complex;
Biological process	dendrite development; COPII vesicle coating; vesicle-mediated transport; endoplasmic reticulum to Golgi vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	51399
	60409
	ENSG00000280495; ENSG00000196655
	ENSMUSG00000032112
	Q9Y296
	Q9ES56
NM_016146; NM_001318486; NM_001318488; NM_001318489; NM_001318490;
	NM_001318492; NM_001318494
	NM_021789
NP_001305415; NP_001305417; NP_001305418; NP_001305419; NP_001305421;
	NP_001305423; NP_057230
	NP_068561
	Wikidata
View/Edit Human	View/Edit Mouse

Trafficking protein particle complex subunit 4 is a protein that in humans is encoded by the TRAPPC4 gene.^[5]^[6] It is part of TRAPP complex.^[7]

References

1 2 3 ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032112 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".
↑ "TRAPPC4 trafficking protein particle complex subunit 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2025-06-02.

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032112 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10810093-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-6] "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".

[7] "TRAPPC4 trafficking protein particle complex subunit 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2025-06-02.

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TRAPPC4

References

Further reading