TMX1

TMX1
Identifiers
Aliases	TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1
External IDs	OMIM: 610527; MGI: 1919986; HomoloGene: 12482; GeneCards: TMX1; OMA:TMX1 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X5E
Enzyme activity
Gene location (Human)
Chr.	Chromosome 14 (human)
End	51,257,655 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	70,514,814 bp
RNA expression pattern
	Top expressed in
	tibia; ; skin of hip; ; mucosa of sigmoid colon; ; germinal epithelium; ; trabecular bone; ; oral cavity; ; skin of thigh; ; jejunal mucosa; ; superficial temporal artery; ; secondary oocyte;
	Top expressed in
	retinal pigment epithelium; ; cumulus cell; ; ciliary body; ; epithelium of lens; ; Paneth cell; ; fossa; ; condyle; ; Epithelium of choroid plexus; ; aortic valve; ; supraoptic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	disulfide oxidoreductase activity; protein disulfide isomerase activity;
Cellular component	integral component of membrane; membrane; endoplasmic reticulum membrane; endoplasmic reticulum;
Biological process	protein folding; response to endoplasmic reticulum stress; cell redox homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	81542
	72736
	ENSG00000139921
	ENSMUSG00000021072
	Q9H3N1
	Q8VBT0
	NM_030755
	NM_028339
	NP_110382
	NP_082615
	Wikidata
View/Edit Human	View/Edit Mouse

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139921 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021072 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi:10.1074/jbc.M011037200. PMID 11152479.
↑ "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi:10.1038/nature01348. PMID 12508121.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139921 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021072 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11152479-5] Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi:10.1074/jbc.M011037200. PMID 11152479.

[entrez-6] "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

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TMX1

References

Further reading