TMEM165

TMEM165
Identifiers
Aliases	TMEM165, CDG2K, FT27, GDT1, TMPT27, TPARL, transmembrane protein 165, SLC64A1, LCI
External IDs	OMIM: 614726; MGI: 894407; GeneCards: TMEM165
Gene location (Human)
Chr.	Chromosome 4 (human)
End	55,453,397 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	76,357,092 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; C1 segment; ; gastric mucosa; ; right lung; ; inferior ganglion of vagus nerve; ; upper lobe of left lung; ; palpebral conjunctiva; ; subthalamic nucleus; ; cartilage tissue; ; monocyte;
	Top expressed in
	molar; ; vestibular sensory epithelium; ; mandibular prominence; ; atrioventricular valve; ; primitive streak; ; endocardial cushion; ; tail of embryo; ; maxillary prominence; ; vas deferens; ; decidua;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	55858
	21982
	ENSG00000134851
	ENSMUSG00000029234
	Q9HC07
	P52875
	NM_018475
	NM_011626
	NP_060945
	NP_035756
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane protein 165 is a protein that in humans is encoded by the TMEM165 gene.^[5] It is found both on the Golgi and in lysosomes. It is also called LCI because it is a proton-activated, lysosomal calcium importer.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000134851 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029234 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Transmembrane protein 165". Retrieved 2011-12-06.
↑ Zajac, M., Mukherjee, S., Anees, P., Oettinger, D., Henn, K., Srikumar, J., Zou, J. Saminathan, A., Krishnan, Y. A mechanism of lysosomal Calcium entry. Sci. Adv. 2024, 10, eadk2317. https://www.science.org/doi/10.1126/sciadv.adk2317

Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, et al. (August 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–9548. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000134851 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029234 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Transmembrane protein 165". Retrieved 2011-12-06.

[6] Zajac, M., Mukherjee, S., Anees, P., Oettinger, D., Henn, K., Srikumar, J., Zou, J. Saminathan, A., Krishnan, Y. A mechanism of lysosomal Calcium entry. Sci. Adv. 2024, 10, eadk2317. https://www.science.org/doi/10.1126/sciadv.adk2317

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TMEM165

References

Further reading