// Workers AI · dad joke modeWhat did TMCO1 say to its friend? "You can count on me.

TMCO1
Identifiers
Aliases	TMCO1, HP10122, PCIA3, PNAS-136, TMCC4, transmembrane and coiled-coil domains 1
External IDs	OMIM: 614123; MGI: 1921173; HomoloGene: 10384; GeneCards: TMCO1; OMA:TMCO1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	165,827,755 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	167,161,547 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; Epithelium of choroid plexus; ; rectum; ; islet of Langerhans; ; jejunal mucosa; ; gallbladder; ; mucosa of colon; ; mucosa of transverse colon; ; bronchial epithelial cell; ; mucosa of sigmoid colon;
	Top expressed in
	right kidney; ; seminal vesicula; ; molar; ; parotid gland; ; left lung lobe; ; spermatocyte; ; decidua; ; submandibular gland; ; atrioventricular valve; ; human kidney;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	calcium channel activity;
Cellular component	membrane; endoplasmic reticulum membrane; Golgi membrane; Golgi apparatus; integral component of membrane; endoplasmic reticulum; integral component of endoplasmic reticulum membrane;
Biological process	calcium ion transport; ER overload response; ion transport; calcium ion transmembrane transport; endoplasmic reticulum calcium ion homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	54499
	68944
	ENSG00000143183
	ENSMUSG00000052428
	Q9UM00
	Q921L3
	NM_001256164; NM_001256165; NM_019026; NM_001366129
	NM_001039483; NM_026881
	NP_001243093; NP_001243094; NP_061899
	NP_001034572
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the TMCO1 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000143183 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052428 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
↑ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
↑ "Entrez Gene: TMCO1 transmembrane and coiled-coil domains 1".

Iwamuro S, Saeki M, Kato S (1999). "Multi-ubiquitination of a nascent membrane protein produced in a rabbit reticulocyte lysate". J. Biochem. 126 (1): 48–53. doi:10.1093/oxfordjournals.jbchem.a022435. PMID 10393320.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000143183 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052428 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8619474-5] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

[pmid9110174-6] Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.

[entrez-7] "Entrez Gene: TMCO1 transmembrane and coiled-coil domains 1".

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// Workers AI · dad joke modeWhat did TMCO1 say to its friend? "You can count on me.

References

Further reading