Sankar Adhya
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Sankar Adhya (born 4 October 1937) is a molecular biologist and geneticist at the National Cancer Institute (NCI)[1] and a member of the National Academy of Sciences.[2] He is best known for his work on bacterial transcription and the biology of bacteriophage lambda. He has made important contributions regarding the physical basis of transcriptional regulation in bacteria, the lysis/lysogeny switch in lambda phage, the organization of the bacterial nucleoid, and phage therapy.
Early life and education
[edit]Adhya was born in Kolkata, India and studied chemistry at the University of Calcutta as an undergraduate. He later obtained a Ph.D. from the University of Calcutta in biochemistry and a second Ph.D. in genetics from the University of Wisconsin–Madison.
Work
[edit]Following postdoctoral training at Stanford University, the Bose Institute, and the University of Rochester, he joined the NCI's newly formed Laboratory of Molecular Biology (LMB) in 1971.[3][4] He has remained at the NIH since 1971 and is presently Head of the LMB's Developmental Genetics section.[1]
Awards and honors
[edit]- Elected to the National Academy of Sciences in 1994.[2]
- Elected to the Indian National Science Academy in 1995.[1]
- Elected to the American Academy of Arts and Sciences in 2009.[1]
- Elected to the Hungarian Academy of Sciences in 2010 as a foreign member.[1]
Selected publications
[edit]- Adhya, S; Gottesman, M (1978). "Control of transcription termination". Annual Review of Biochemistry. 47 (1): 967–996. doi:10.1146/annurev.bi.47.070178.004535. PMID 354508.
- Irani, M; Orosz, L; Adhya, S (1983). "A control element within a structural gene: the gal operon of Escherichia coli". Cell. 32 (3): 783–788. doi:10.1016/0092-8674(83)90064-8. PMID 6299576. S2CID 41077642.
- Adhya, S (1989). "Multipartite genetic control elements: communication by DNA loop". Annual Review of Genetics. 23 (1): 227–250. doi:10.1146/annurev.ge.23.120189.001303. PMID 2694932.
- Merril, C; Biswas, B; Carlton, R; Jensen, N; Creed, G; Zullo, S; Adhya, S (1996). "Long-circulating bacteriophage as antibacterial agents". Proceedings of the National Academy of Sciences. 93 (8): 3188–3192. Bibcode:1996PNAS...93.3188M. doi:10.1073/pnas.93.8.3188. PMC 39580. PMID 8622911.
- Merril, C; Scholl, D; Adhya, S (2003). "The prospect for bacteriophage therapy in Western medicine". Nature Reviews Drug Discovery. 2 (6): 489–497. doi:10.1038/nrd1111. PMID 12776223. S2CID 23298353.
- Oppenheim, A; Kobiler, O; Stavans, J; Court, D; Adhya, S (2005). "Switches in bacteriophage lambda development". Annual Review of Genetics. 39 (1): 409–429. doi:10.1146/annurev.genet.39.073003.113656. PMID 16285866.
References
[edit]- 1 2 3 4 5 "Sankar Adhya Ph.D." National Cancer Institute. Retrieved 17 November 2016.
- 1 2 "Sankar Adhya". National Academy of Sciences. Retrieved 17 November 2016.
- ↑ Adhya, Sankar; Gant, Jason (1 October 2008). "NCI Laboratory of Molecular Biology Oral History Project" (PDF). Archived from the original (PDF) on 26 November 2010.
- ↑ Adhya, Sankar; Gant, Jason (8 October 2008). "NCI Laboratory of Molecular Biology Oral History Project" (PDF). Archived from the original (PDF) on 26 November 2010.
| Authority control databases: Academics |
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- Indian molecular biologists
- Genetic epidemiologists
- American geneticists
- Living people
- University of Calcutta alumni
- Stanford University postdoctoral scholars
- University of Wisconsin–Madison College of Agricultural and Life Sciences alumni
- 1937 births
- Members of the United States National Academy of Sciences
- Foreign fellows of the Indian National Science Academy
- Fellows of the American Academy of Microbiology