STYK1

STYK1
Identifiers
Aliases	STYK1, NOK, SuRTK106, serine/threonine/tyrosine kinase 1
External IDs	OMIM: 611433; MGI: 2141396; GeneCards: STYK1
Enzyme activity EC # BRENDA ExPASy KEGG MetaCyc 2.7.10.2 ↗ ↗ ↗ ↗
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.2 Start 10,618,923 bp End 10,674,318 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 F3 Start 131,276,105 bp End 131,330,560 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell amniotic fluid pancreatic ductal cell rectum middle temporal gyrus Brodmann area 23 mucosa of colon mucosa of transverse colon mucosa of sigmoid colon palpebral conjunctiva Top expressed in zygote jejunum left colon secondary oocyte primary oocyte duodenum Paneth cell ileum granulocyte epithelium of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein tyrosine kinase activity signaling receptor binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity Cellular component integral component of membrane extrinsic component of cytoplasmic side of plasma membrane plasma membrane membrane Biological process peptidyl-tyrosine autophosphorylation cell differentiation protein phosphorylation innate immune response cell migration regulation of cell population proliferation phosphorylation chemotaxis cell adhesion epidermal growth factor receptor signaling pathway regulation of mast cell degranulation peptidyl-tyrosine phosphorylation Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 55359 243659 Ensembl ENSG00000060140 ENSMUSG00000032899 UniProt Q6J9G0 Q6J9G1 RefSeq (mRNA) NM_018423 NM_172891 RefSeq (protein) NP_060893 NP_766479 Location (UCSC) Chr 12: 10.62 – 10.67 Mb Chr 6: 131.28 – 131.33 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Tyrosine-protein kinase STYK1 is an enzyme that in humans is encoded by the STYK1 gene.

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liu L, Yu XZ, Li TS, et al. (2004). "A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice". Cancer Res. 64 (10): 3491–9. doi:10.1158/0008-5472.CAN-03-2106. PMID 15150103.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Amachika T, Kobayashi D, Moriai R, et al. (2007). "Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers". Lung Cancer. 56 (3): 337–40. doi:10.1016/j.lungcan.2007.01.002. PMID 17298854.