Probable low affinity copper uptake protein 2

SLC31A2
Identifiers
Aliases	SLC31A2, COPT2, CTR2, hCTR2, solute carrier family 31 member 2
External IDs	OMIM: 603088; MGI: 1333844; GeneCards: SLC31A2
Gene location (Human) Chr. Chromosome 9 (human) Band 9q32 Start 113,150,976 bp End 113,164,140 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 B3 Start 62,180,799 bp End 62,216,648 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland inferior ganglion of vagus nerve C1 segment corpus callosum pons subthalamic nucleus medulla oblongata monocyte superior vestibular nucleus decidua Top expressed in lacrimal gland seminal vesicula parotid gland neural layer of retina granulocyte spermatid submandibular gland renal corpuscle lip gastrula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function copper ion transmembrane transporter activity Cellular component integral component of membrane recycling endosome late endosome integral component of plasma membrane membrane plasma membrane Biological process copper ion transport ion transport copper ion transmembrane transport regulation of copper ion transmembrane transport cellular copper ion homeostasis Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 1318 20530 Ensembl ENSG00000136867 ENSMUSG00000066152 UniProt O15432 Q9CPU9 RefSeq (mRNA) NM_001860 NM_001290518 NM_025286 RefSeq (protein) NP_001851 NP_001277447 NP_079562 Location (UCSC) Chr 9: 113.15 – 113.16 Mb Chr 4: 62.18 – 62.22 Mb PubMed search
Wikidata
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Probable low affinity copper uptake protein 2 is a protein that in humans is encoded by the SLC31A2 gene.

See also

• Solute carrier family

Further reading

• Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• van den Berghe PV, Folmer DE, Malingré HE, van Beurden E, Klomp AE, van de Sluis B, Merkx M, Berger R, Klomp LW (2007). "Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake". Biochem. J. 407 (1): 49–59. doi:10.1042/BJ20070705. PMC 2267400. PMID 17617060.