// Workers AI · dad joke modeWhat did PMP34 say? I'm pumped to be a membrane protein.

SLC25A17
Identifiers
Aliases	SLC25A17, PMP34, solute carrier family 25 member 17
External IDs	OMIM: 606795; MGI: 1342248; HomoloGene: 4637; GeneCards: SLC25A17; OMA:SLC25A17 - orthologs
Gene location (Human) Chr. Chromosome 22 (human) Band 22q13.2 Start 40,769,630 bp End 40,819,399 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 E1 Start 81,203,112 bp End 81,245,013 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ovary right ovary islet of Langerhans body of uterus ganglionic eminence right adrenal cortex gonad left adrenal gland ventricular zone parotid gland Top expressed in right kidney superior surface of tongue gallbladder ventricular zone esophagus yolk sac corneal stroma proximal tubule choroid plexus of fourth ventricle lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function chaperone binding ATP transmembrane transporter activity AMP transmembrane transporter activity ADP transmembrane transporter activity FMN transmembrane transporter activity coenzyme A transmembrane transporter activity NAD transmembrane transporter activity FAD transmembrane transporter activity protein binding adenine nucleotide transmembrane transporter activity transmembrane transporter activity Cellular component cytoplasm integral component of membrane membrane peroxisomal membrane peroxisome mitochondrion integral component of peroxisomal membrane mitochondrial inner membrane Biological process ATP transport fatty acid transport transmembrane transport fatty acid alpha-oxidation fatty acid beta-oxidation ADP transport coenzyme A transmembrane transport NAD transport AMP transport FAD transmembrane transport nucleotide transmembrane transport mitochondrial transport transport NAD transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10478 20524 Ensembl ENSG00000100372 ENSMUSG00000022404 UniProt O43808 O70579 RefSeq (mRNA) NM_001282726 NM_001282727 NM_006358 NM_011399 RefSeq (protein) NP_001269655 NP_001269656 NP_006349 NP_035529 Location (UCSC) Chr 22: 40.77 – 40.82 Mb Chr 15: 81.2 – 81.25 Mb PubMed search
Wikidata
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Peroxisomal membrane protein PMP34 is a protein that in humans is encoded by the SLC25A17 gene.

Function

SLC25A17 is a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers.[supplied by OMIM]

See also

• Solute carrier family

Further reading

• Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (December 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
• Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (March 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". The Journal of Cell Biology. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
• Honsho M, Fujiki Y (March 2001). "Topogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34". The Journal of Biological Chemistry. 276 (12): 9375–82. doi:10.1074/jbc.M003304200. PMID 11121399.
• Jones JM, Morrell JC, Gould SJ (June 2001). "Multiple distinct targeting signals in integral peroxisomal membrane proteins". The Journal of Cell Biology. 153 (6): 1141–50. doi:10.1083/jcb.153.6.1141. PMC 2192020. PMID 11402059.
• Visser WF, van Roermund CW, Waterham HR, Wanders RJ (December 2002). "Identification of human PMP34 as a peroxisomal ATP transporter". Biochemical and Biophysical Research Communications. 299 (3): 494–7. doi:10.1016/S0006-291X(02)02663-3. PMID 12445829.
• Jones JM, Morrell JC, Gould SJ (January 2004). "PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins". The Journal of Cell Biology. 164 (1): 57–67. doi:10.1083/jcb.200304111. PMC 2171958. PMID 14709540.
• Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biology. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.