RNF26

RNF26
Identifiers
Aliases	RNF26, ring finger protein 26
External IDs	OMIM: 606130; MGI: 2388131; HomoloGene: 12924; GeneCards: RNF26; OMA:RNF26 - orthologs
Enzyme activity EC # BRENDA ExPASy KEGG MetaCyc 2.3.2.27 ↗ ↗ ↗ ↗
Gene location (Human) Chr. Chromosome 11 (human) Band 11q23.3 Start 119,334,527 bp End 119,337,309 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A5.1 Start 44,006,928 bp End 44,024,814 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum ventricular zone stromal cell of endometrium mucosa of transverse colon smooth muscle tissue prefrontal cortex right coronary artery popliteal artery tibial arteries body of stomach Top expressed in tracheobronchial tree trachea choroid plexus choroid plexus of fourth ventricle embryonic cell zygote primary motor cortex medulla oblongata pons secondary oocyte More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding protein binding zinc ion binding ubiquitin protein ligase activity transferase activity Cellular component integral component of membrane membrane endoplasmic reticulum endoplasmic reticulum membrane Biological process endosome organization regulation of type I interferon production negative regulation of defense response to virus protein K11-linked ubiquitination protein localization to perinuclear region of cytoplasm protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79102 213211 Ensembl ENSG00000173456 ENSMUSG00000053128 UniProt Q9BY78 Q8BUH7 RefSeq (mRNA) NM_032015 NM_153762 RefSeq (protein) NP_114404 NP_717095 Location (UCSC) Chr 11: 119.33 – 119.34 Mb Chr 9: 44.01 – 44.02 Mb PubMed search
Wikidata
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Ring finger protein 26 is a protein that in humans is encoded by the RNF26 gene.

Function

The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008].

Further reading

• Katoh M (April 2001). "Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper". Biochemical and Biophysical Research Communications. 282 (4): 1038–44. doi:10.1006/bbrc.2001.4671. PMID 11352657.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.