RAB37

RAB37
Identifiers
Aliases	RAB37, member RAS oncogene family
External IDs	OMIM: 609956; MGI: 1929945; HomoloGene: 23303; GeneCards: RAB37; OMA:RAB37 - orthologs
Enzyme activity
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,747,335 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,053,062 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; granulocyte; ; monocyte; ; blood; ; nasal epithelium; ; spleen; ; bone marrow cell; ; right lobe of liver; ; endothelial cell;
	Top expressed in
	islet of Langerhans; ; granulocyte; ; lateral geniculate nucleus; ; anterior horn of spinal cord; ; medial dorsal nucleus; ; medial geniculate nucleus; ; retinal pigment epithelium; ; cerebellar cortex; ; facial motor nucleus; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasmic vesicle; endoplasmic reticulum-Golgi intermediate compartment; azurophil granule membrane; specific granule membrane; endosome; plasma membrane; synaptic vesicle; secretory granule membrane; intracellular anatomical structure;
Biological process	protein transport; neutrophil degranulation; vesicle docking involved in exocytosis; protein secretion; protein localization to plasma membrane; regulation of exocytosis; intracellular protein transport; Rab protein signal transduction; small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	326624
	58222
	ENSG00000172794
	ENSMUSG00000020732
	Q96AX2
	Q9JKM7
NM_001006637; NM_001006638; NM_001163989; NM_001163990; NM_175738;
	NM_001330471
	NM_001163753; NM_021411
	NP_001006639; NP_001157461; NP_001157462; NP_001317400; NP_783865
	NP_001157225; NP_067386
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.^[5]^[6]

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172794 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020732 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.
1 2 "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000172794 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020732 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10722846-5] Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.

[entrez-6] 1 2 "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

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RAB37

References

Further reading