// Workers AI · dad joke modeWhat did patchoulol synthase say? "I'm patched in
| Patchoulol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.70 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Patchoulol synthase (EC 4.2.3.70) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + H2O patchoulol + diphosphate
References
[edit]- ↑ Croteau R, Munck SL, Akoh CC, Fisk HJ, Satterwhite DM (July 1987). "Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations". Archives of Biochemistry and Biophysics. 256 (1): 56–68. doi:10.1016/0003-9861(87)90425-5. PMID 3038029.
- ↑ Munck SL, Croteau R (October 1990). "Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin". Archives of Biochemistry and Biophysics. 282 (1): 58–64. doi:10.1016/0003-9861(90)90086-e. PMID 2171435.
- ↑ Faraldos JA, Wu S, Chappell J, Coates RM (March 2010). "Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase". Journal of the American Chemical Society. 132 (9): 2998–3008. Bibcode:2010JAChS.132.2998F. doi:10.1021/ja909251r. PMID 20148554.
External links
[edit]- Patchoulol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
